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000). The demographic, clinical and laboratory data of the renal lupus group are given in Table 1. Using Chi square test, no significant association could be detected between Y chromosome microchimerism and different classes of renal biopsy specimens, ��2?=?5.0, p?=?0.28. On the other hand, the association between microchimerism and SLICC damage index among women with cutaneous lupus (p?=?0.02) was not strong as that in the microchimeric renal group. Table 2 shows the demographic, clinical and laboratory variables of cutaneous lupus patients. Anticardiolipin antibodies were not significantly associated with the presence of microchimerism in both renal and cutaneous lupus females, ��2?=?2.3, p?=?0.12 and ��2?=?0.18, p?=?0.66, respectively. Fleroxacin The microchimeric renal lupus patients were characterized by significant increase in age, age at disease diagnosis, disease duration, t?=?6.6, 5.6, 6.2 (p?click here mothers to at least one live birth son, 10 women gave history of at least one abortion. Ten patients gave birth to at least one daughter and three females did not report any pregnancy. All females with live birth sons, abortions and three patients Luminespib cell line out of 10 with daughters were microchimeric. Regarding cutaneous lupus group, three patients had at least one live birth son, while five women reported at least one abortion, eight patients had given birth to at least one daughter and nine females reported no history of pregnancy. All women who gave history of having live birth sons and abortions were microchimeric. Moreover those with daughters or gave no history of pregnancy were not microchimeric. Microchimerism was significantly associated with increased number of pregnancies among the renal lupus group (Table 1). Meanwhile, this association could not be detected in the cutaneous lupus group (Table 2). In addition, a significant increase in the number of pregnancies, abortions and age of the oldest son were detected on investigating microchimeric women with renal lupus against microchimeric cutaneous lupus females. Furthermore the difference between both groups regarding the number of live birth sons had approached statistical significance (Table 3). The mean number of pregnancies, live birth sons, abortions and age of the oldest son were significantly higher, t?=?7.2 (p?