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The demographic characteristics of women who had a live birth in their first pregnancy and then went on to have an IA, a live birth or a miscarriage in their second pregnancy are shown in table 3. Women with an IA in their second pregnancy were younger, belonged to a more deprived social group and were more likely to be smokers than women who had a live birth in their second pregnancy. Compared with women who had a miscarriage in their second pregnancy, women with a previous IA were older, belonged to more deprived social classes and were more likely to smoke. Table 3 Demographic characteristics of women who had induced abortion, live birth or miscarriage after an initial live birth As table 4 shows, IA in the second pregnancy was associated with a higher risk of an ectopic pregnancy or an IA in the third pregnancy compared with an initial live birth. The risk of miscarriage see more in a third pregnancy was lower in women who had an IA in their second pregnancy, but the risks of another IA were higher than in women with a previous miscarriage. Table 4 Reproductive and perinatal outcomes in women who had induced abortion, live birth or miscarriage following a live birth in the first pregnancy Compared with women with two previous live births, women with a live birth followed by an IA were more likely to have pre-eclampsia, placenta praevia, induced labour, low birth weight and spontaneous preterm, very preterm and extremely preterm birth (table 4). Women with an IA in their second pregnancy were not at any significantly higher risk of perinatal complications Rho kinase inhibition in comparison with women with a previous miscarriage. In records Non-specific serine/threonine protein kinase where the method of IA was clearly recorded, 52?560 women were noted to have had surgical and 16?702, medical abortions. As table 5 shows, reproductive outcomes were comparable in the two groups except for a lower risk of a second IA following surgical termination of pregnancy. The adjusted RR of miscarriage, ectopic pregnancy, placenta praevia and spontaneous preterm delivery (