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Improved: 100% relief of signs and symptoms Markedly improved: Improvement between >75% and 99% Moderately improved: Improvement between >50% and 75% Mild improvement: Improvement between 25% and 50% Unchanged: No relief in signs and symptoms. Peak Flow Meter and Spirometry was carried out to those who can perform the test to explore the condition. The follow-up period was of 8 weeks, with fortnight intervals of patient selleck inhibitor visit for any recurrence of symptoms of Tamaka Shwasa. Statistical analysis Comparative efficacy in group AG and VG was assessed by applying the unpaired Student's t-test. Observations Total 74 patients completed the course of treatment. In group Ashtangavaleha (AG), 36 patients while in group Vyaghreehareetakee Avaleha (VG), 38 patients completed the course of treatment. In general obcservations out of 100, maximum number of patients that is 27% belonged to 5-7 years age group, 71% male, 87% of Hindu religion, 48% were from middle group of socioeconomic status. In chief complaints Shwaskashtata (breathlessness), Kasa (cough) and Peenas was noted in 100% patient. Ghurghurakam (audible breathing) was complained by 90% patients, expectoration was noted in 70% of patients, 64% patients reported disturbed sleep and Urah-Parshwa Peeda (chest pain/chest tightness). Chronicity of Tamaka Shwasa (1-5 years) was noted in 65% of patients, family history of asthma was NK cell reported in 69% patients. Results Effect on cardinal symptoms of Tamaka Shwasa The variations in the effects of selleckchem Ashtangavaleha and Vyaghreehareetakee Avaleha on the symptoms of Tamaka Shwaasa were statistically insignificant except in cough in which the comparator agent showed better result, which was statistically significant [Table 1]. Table 1 Comparative effect on symptoms of Tamaka Shwasa The variations in the effects of intervention and comparator agents on Asthma Control Questioner (ACQ) assessments were statistically insignificant except in awakening in night due to asthma (