Identifying The Most Efficient Obeticholic Acid Is Not Hard

Total EDSS scores were significantly correlated with sway path length in the EO (P Dolutegravir cell line subscore of 1 or greater, and cerebellar subscores and total EDSS scores were significantly correlated (r = 0.544, P Selleckchem Obeticholic Acid correlation between total EDSS scores and trunk sway with EC (r = 0.542). However, unlike in the present study, they did not find a significant correlation with EO sway. This inconsistency may be explained by the different measures of postural sway (pitch and roll angle and velocity range vs. total path length), the different devices (digital gyroscope worn on the lumbar spine vs. CDK9 three-dimensional motion capture marker at C7), and the different standing positions (feet shoulder-width apart vs. feet together).12 Analysis of the EDSS subscores revealed that cerebellar subscores were associated with increased postural sway in the EO and EC conditions. These results are not surprising, as patients with cerebellar ataxia have difficulties scaling their postural responses in stance, resulting in overcorrective, hypermetric movements.30 Demyelination in the cerebellum is prominent in people with MS,31 and lesions in the brainstem and cerebellum have been shown to be associated with increased sway and number of falls over a 6-month period.32 Standing sway measures have previously been shown to be positively correlated with gray and white matter lesions in the cerebellum and its connections as measured using magnetic resonance imaging in people with MS.33 Sway with EO has also been shown to be associated with cerebellar atrophy in people with MS.