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Setting and Sample Population?�C? The sample consisted of 252 subjects with ages ranged from 13 to 30?years. Materials and Methods?�C? Images of dental casts were captured by stereophotogrammetry and selected variables were measured using a three-dimensional (3D) imaging system. Sex differences and changes associated with age were assessed, and interrelationships between different variables were explored within the study group. Results?�C? Men had significantly larger mesio-distal crown widths and dental arch dimensions than women (p?check details the dental arch dimensions or mesio-distal crown widths showed a significant change because of age except the widths of the upper canine, lower first molar and central incisor. Significant correlations of tooth size with dental arch dimensions were found, particularly with arch lengths and perimeters. A principal component analysis showed interrelationships between the majority of tooth size variables with inter-canine width, arch length and perimeter distances. Conclusion?�C? This study has established new GABA activity reference data for tooth size and arch dimensions in Malays and demonstrated patterns of variation that are relevant to anthropologists interested in making comparisons within and between different populations and also to clinicians developing treatment plans for their patients. The study confirmed the accuracy of the 3D photogrammetric method for measuring dental casts. ""To cite this article: Uysal T, Amasyali M, Enhos S, Karslioglu Y, Yilmaz F, Gunhan O: Effect of periosteal stimulation therapy on bone formation in orthopedically expanded suture in rats Orthod Craniofac Res 2010;13:89�C95 Authors?�C? Uysal T, Amasyali M, Enhos S, Karslioglu Y, Yilmaz F, Gunhan O Objective?�C? The aim of this experimental study was to evaluate the effects of periosteal stimulation therapy (PST), on bone regeneration in response to expansion of the interpremaxillary suture, in rats. Material and Methods?�C? Sixteen male, 50�C60?days old Wistar rats were divided ALG1 into two equal groups (control and experimental). Both groups were subjected to expansion for 5?days, and 30?cN of force was applied to the maxillary incisors with helical spring. On the 2nd day of the expansion procedure in the experimental group, the periosteum over the interpremaxillary suture was stimulated locally by intraperiosteal penetrations with a hypodermic needle. Bone regeneration in the interpremaxillary suture was evaluated by bone histomorphometry and the new bone area, bone perimeter, feret��s diameter and new bone/old bone percentage parameters were evaluated. Mann�CWhitney U-test was used for statistical evaluation at p?