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According to the human literature, cysts of the CBD require treatment because of their common association with cholangitis, pancreatitis, and cystic rupture. We were unable to confirm a link between the cyst and cholangitis in this case. It is possible that detection of this anomaly was an incidental finding unrelated to bacterbilia. Histological examination of cyst tissue is mandatory for a definitive diagnosis and to differentiate it from neoplasia. This is the first description of a cyst of the CBD in the cat. ""Objective? To compare the efficacy of the non-steroidal antiinflammatory drugs, diclofenac sodium and flunixin meglumine as adjuncts to the antibiotic treatment Selleck Erastin of bovine respiratory disease (BRD). Procedure? We randomly allocated 80 Holstein calves with BRD to three groups. All the calves received a dose of 2.5?mg/kg tulathromycin by single subcutaneous injection and two of the groups thiram received, in addition, either 2.5?mg/kg diclofenac sodium as a single intramuscular injection (diclofenac group, n?=?30) or 2.2?mg/kg flunixin meglumine as an intravenous injection on the first three consecutive days after tulathromycin administration (flunixin group, n?=?30). All calves were given a clinical score prior to initial treatment (day 0) and after treatment (days 1, 2, 3, 7 and 14) by observing appetite, demeanour, rectal temperature, the rate and type of respiration, presence or absence of coughing, and nasal discharge. Results? During the first 48?h, improvement of adverse signs of respiratory disease, such as pyrexia and elevated respiratory rate, and of a high clinical index score was significant in the two adjunct groups compared with the calves receiving antibiotic alone. The reduction in pyrexia was greatest in the diclofenac group. There were no statically significant differences 3-deazaneplanocin A research buy between treatment groups with regard to eventual perceived recovery from respiratory disease in 14 days. Conclusion? In this trial, a single intramuscular dose of diclofenac sodium was equally effective as three intravenous injections of flunixin meglumine given on consecutive days as adjunctive therapy for BRD. ""A lack of information limits understanding of the excess cat problem and development of effective management strategies. This study describes cats entering Royal Society for the Prevention of Cruelty to Animals (RSPCA) Queensland shelters and identifies risk factors for euthanasia. Data for cats entering relevant shelters (July 2006�CJune 2008) were obtained from the RSPCA's electronic database. Univariable and multivariable logistic regression analyses were conducted to identify risk factors for euthanasia. Of 33,736 cats admitted, 46% were adult cats (��3 months) and 54% were kittens (