S6 Kinase Earns Absolutely Free Kickstart... By A Social Activity Ensemble!!

Матеріал з HistoryPedia
Перейти до: навігація, пошук

Results Establishing animal models Based on the standard dog model of acute TBI, we successfully created 18 models in this study. Among these animals, 1 died at 10 h after the injury, 2 died after 1 day, and 15 survived until 3 days after the injury. RTMCE results before and after the injury A total of 50-70 images that were recorded after ultrasonic destruction of the microbubbles were selected, and 2-5 regions of interest (their size was consistent with inner end-diastolic wall thickness) were selected based on the extent of the lesion. Compared to those before the injury, the post-injury levels of LY294002 A, ��, and A���� decreased significantly in 4 myocardial segments of the anterior and inferior left ventricle wall in 3 mongrel dogs at 6 h. At 1 and 3 days after the injury, the levels of A, ��, and A���� decreased significantly in 29 myocardial segments, compared to the pre-injury values (P S6 Kinase the diastolic strain rates were positive, and the tone transitioned from cyan to blue for increasingly positive strain rates. The 3 major peaks in the strain rate-time curve (i.e., the S, E, and A peaks) had clear outlines. The color of each injured myocardial segment gradually decreased from 6 h to 3 days after the injury, and exhibited irregular variations. The color in a few segments was pure green, and the strain rate-time curve Lapatinib lost its normal shape and exhibited an irregular outline (Figure 2). Figure 2 Long-axis imaging of the left ventricle at 1 day after the injury: no variations are observed in the color of the regional myocardium, and the strain rate-time curve is disordered (A) strain rate recorded before TBI, (B) images of 1day after TBI. The crests of the S, E, and A peaks were very small and subsequently disappeared, and the peak values were significantly lower than those obtained before the injury (P