The Hard Fact Of DDR1

Admission to intensive care unit (ICU) in patients with cancer would make some distress in emotion and quality of life. The decision making is difficult to admit ICU in lung cancer patient. The predictive factors of outcome will be needed. We reviewed the clinical outcome and characteristics of patients with lung cancer who admitted ICU retrospectively. Methods?We retrospectively collected clinical data of patients with lung cancer who admitted ICU from January 2010 to November 2011. Causes of admission, use of mechanical ventilation, presence of do-not-resuscitate, mortality were included. Postsurgical care was excluded in analysis. Results?One hundred thirty one patients were admitted in ICU. For postoperative care ninety three DDR1 patients were admitted in surgical ICU and excluded. We analyzed thirty eight patients of lung cancer. NSCLC patients were 34 (89%) and SCLC patients 4 (11%). 25 patients (66%) were inoperable stage (stage IIIB, IV). Causes of admission were acute respiratory failure (78%), cardiovascular disease (8%), gastrointestinal bleeding (8%) and neurologic disease (5%). The mortality of ICU was 53% (20/38). Seventeen patients and family noticed the code of do-not-resuscitation after ICU admission. Twenty nine (79%) patients were received mechanical ventilation and 25 of 29 patients were dead during ICU care. Conclusion?In advanced lung cancer patients, ICU care would not be selleck chemicals llc needed in some conditions. The model of ICU mortality in lung cancer should be established for the purpose of well-dying care. JYI LIN WONG1, SIEW TECK TIE1, KONG LEONG YU2, PEY JIE VOON2 1Department of Medicine, Sarawak General Hospital, 2Onoclogy Unit, Sarawak selleck products General Hospital Introduction?Incidence of lung malignancy is rising due to prevalence of smoking. Adenocarcinoma is the most common histological subtype worldwide and in Malaysia. Its treatments have evolved from the conventional chemotherapy to targeted therapy. EGFR mutation is an established predictive factor for the use of tyrosine kinase inhibitor (TKI). While EGFR mutation has been more commonly associated with Asians, its prevalence among different ethnic group among Asians has not be established. Methods?A retrospective study. All patients seen in respiratory unit between Nov 2011 to Feb 2013 whom were suffering from lung malignancy were included. Their characteristics were obtained from clinic cards. Results?A total of 93 patient was included in the analysis. Adenocarcinoma was found in 53% (n?=?49) of the cases and squamous cell carcinoma in 25% (n?=?23) of the cases. Overall, lung carcinoma suffers are more likely to be male (69%, n?=?64) and smokers (56% n?=?52). However, for subtype adenocarcinoma female (OR 2.48 p?=?0.048) and non-smokers (OR 7.09, p?