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05 were considerate as statistically significant. Tab. 1 presents about 70 ingredients of EEP. Caffeic acid phenethyl ester (CAPE) and chrysin, considered as the major active compounds of the propolis, compose about 0.6 % and 2.3 %, respectively. 24 h after treatment all tested concentrations of freeze dried EEP dissolved in DMSO and then diluted in MEM (10, 20, 30, 50, 100 ��g/ml) significantly decreased the viability of astrocytes (Fig.1). The maximum inhibition of growth was observed Cilengitide after application of EEP at the highest concentration (100 ��g/ml). Similarly, 48 h after of exposition to EEP viability of astroglia cells was markedly decreased in concentration dependent manner and reached about 6.91 % when 100 ��g/ml of EEP was used. Very strong inhibition of astrocytes growth was observed 72 h after exposition to EEP. After application of 50 and 100 ��g/ml of EEP the highest reduction of astroglia cells viability was noted. The correlation between growth of astrocytes and concentrations of EEP (r = �C0.7370; p Everolimus of 10 ��M. The decline of viability of astrocytes was observed dependently on the concentration of tested substance 48 h after application to SVGp12 cells. The strongest reduction of survivability of cells was noted after using of 50 ��M of chrysin. see more Similarly, inhibition of astrocytes growth 72h after of exposition to chrysin at concentration of 10 ��M, 20 ��M and 30 ��M, and 50 ��M was observed. We showed strong negative correlation (r =�C0.91; p