The Problems You Havent Read About EX 527

National population statistics and dates of death were retrieved from the National Registry. During the study period, 692 individuals from 19 institutions had 721 distinct episodes of S.?aureus bacteraemia. The incidence rose from 22.7 to 28.9 per 100?000 per year during the period (p?0.012). Epigenetics inhibitor Nosocomial infections comprised 46.3% of cases, 14.6% were healthcare-associated, and 39.1% were community-acquired. The proportion of nosocomial infections decreased during the period (p?Vatalanib (PTK787) 2HCl era, and today the infection still carries a significant risk of morbidity and mortality [13]. Reported mortalities generally range from 11% to 40% in developed countries [2�C4,12,14�C18]. However, most studies have been institution-based rather than population-based, and have rarely assessed long-term outcome [16,19,20]. Despite the importance of the infection, few data have been published regarding temporal changes in the incidence and mortality of SAB [2�C4,9,11,14,17]. The objective of the present study was to evaluate trends in the incidence, short-term mortality and long-term mortality of SAB in Iceland during 1995�C2008. A second objective was to assess the proportions of nosocomial and healthcare-associated infections and trends in antimicrobial susceptibility. buy Docetaxel Iceland is an island in the North Atlantic Ocean with an area of 103?000?km2 and a population of just over 300?000. The majority of inhabitants live in the south-west, around the capital. The healthcare system is run by the government, with a university hospital in Reykjavik and a teaching hospital in Akureyri. Smaller regional hospitals are spread around the country. Cases of SAB occurring between 1 January 1995 and 31 December 2008 were identified retrospectively by clinical microbiological laboratories that perform blood cultures in Iceland. All collected blood cultures in the country are sent to one of two laboratories. Individuals 18?years or older with a positive blood culture for S.?aureus were included.