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5?months post-loading. Between insertion and loading mean bone loss was 0.50?mm (SD?��?0.40) and between loading and 12-months a bone gain of 0.12?mm (SD?��?0.42) was observed. Preliminary data also confirm this trend between loading and 24?months. Conclusion and clinical implications The CONELOG? SCREW-LINE implant is safe and reliable for the partially edentulous patient in the distal mandible with a good performance regarding Adenylyl cyclase implant survival, esthetical outcome and nearly negligible bone resorption within the first year. ""G. Esteve, L. Esteve University Miguel Hern��ndez of Elche (Alicante), Alicante, Spain Background After tooth loss, the alveolar bone heals with a ridge collapse. Due to the location of the alveolus, the major changes of this process GS-7340 in vitro are in its outer bone wall. As a result, a sloped crest configuration is usually seen, with a vertical discrepancy of 1�C2?mm between the lingual and buccal walls. It is well known that implant shoulder must be located in an optimal relationship with the bone margin, and that the implant axis must be as close to that required by the prosthesis. This situation can be overcome by different therapeutic options, but all of them suboptimal: 1.Placing the implant deeper: implant shoulder at the level of the buccal bone, resting it subcrestal regarding the lingual-palatal wall. 2.Placing the implant at the lingual level and regenerate the exposed threads on the buccal aspect using a membrane and biomaterials. Aim/Hypothesis To evaluate the clinical outcome and periimplant tissue changes of a recent marketed implant, with a shoulder configuration adapted to the sloped bone crest. Material and methods Eight learn more patients with single edentulism were selected for this study. Their crests have to be type B or Ban according to the Misch classification. All the patients included in the present series have and good general health condition. Extractions were carried out between three and 6?months before implant surgery. Implants used were Osseospeed ProfileTM from Dentsply Implants, with different sizes depending on the clinical case. Prosthetic Rehabilitations were performed through customized Titanium abutments (AtlantisTM) and cemented crowns. All the treatments were performed by the same operator (GEP). Radiographic registers, 2D and 3D, were acquired with Sirona OrthoPlus 3D equipment. Photographic records were done by means of a Canon 7D camera, equipped with a EF-60?mm f/2.8 macro lens and a ring flash light. The mean follow-up period of the included cases was 12.8?months. The minimum inclusion criteria was 12?months of follow-up after implantation. Results All the patients were successfully rehabilitated. No implant site showed inflammatory signs. The measured radiographic marginal bone loss was