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(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
- 13:54, 7 вересня 2018 (різн. • історія) . . (+5412) . . Н In line with previous observationsour results further strengthen the concept of selective preservation (In line with previous observationsour results further strengthen the concept of selective preservation) (поточна)
- 10:49, 9 серпня 2018 (різн. • історія) . . (+5593) . . Н Differential methylation of the two CpG dinucleotides within the gives rise to obligatory of preference transcription (Differential methylation of the two CpG dinucleotides within the gives rise to obligatory of preference transcription) (поточна)
- 08:53, 5 липня 2018 (різн. • історія) . . (+4657) . . Н Gland density was measured by counting the number of mucus pockets after carbachol stimulation for areas randomly (Gland density was measured by counting the number of mucus pockets after carbachol stimulation for areas randomly) (поточна)
- 06:37, 5 травня 2018 (різн. • історія) . . (+4384) . . Н Among its several steps SIRT1 activates PGC-1a by way of deacetylation leading to transcriptional activation of a enhance of genes (Among its several steps SIRT1 activates PGC-1a by way of deacetylation leading to transcriptional activation of a enhance of genes) (поточна)
- 06:47, 2 травня 2018 (різн. • історія) . . (+4387) . . Н Between its many steps SIRT1 activates PGC-1a via deacetylation top to transcriptional activation of a enhance of genes (Between its many steps SIRT1 activates PGC-1a via deacetylation top to transcriptional activation of a enhance of genes) (поточна)
- 08:16, 12 квітня 2018 (різн. • історія) . . (+4396) . . Н This narrow cleft promoting fragrant and polar interactions appears well suited to accommodate tiny compounds (This narrow cleft promoting fragrant and polar interactions appears well suited to accommodate tiny compounds) (поточна)
- 11:51, 2 квітня 2018 (різн. • історія) . . (+4358) . . Н Initially it was proposed that the methyl team is oriented but much more current crystal composition elucidations (Створена сторінка: Our study also supplies the very first data on the regulation of PRL technique parts in mammary tissue of CORT-KO and SST-KO mice. Exclusively, we observed that...) (поточна)
- 11:37, 2 квітня 2018 (різн. • історія) . . (+4346) . . Н This was partly described presently divided the binding pocket as the methyl in the oxathiin ring of carboxin (Створена сторінка: Nevertheless, remedy with PCI-24781 for forty eight h can drastically lower the cell viability in SK-N-SH but not in HS-68. Even though CI- 994 treatment method...) (поточна)
- 11:38, 30 березня 2018 (різн. • історія) . . (+4176) . . Н This was partly explained currently divided the binding pocket as the methyl in the oxathiin ring of carboxin (This was partly explained currently divided the binding pocket as the methyl in the oxathiin ring of carboxin) (поточна)
- 13:52, 29 березня 2018 (різн. • історія) . . (+4415) . . Н In carboxin SQR co-crystal buildings the orientation of the methyl team of the oxathiin ring was a subject of controversy (Створена сторінка: The NrpS [http://www.abmole.com/products/pf-04217903.html PF-4217903] protein is generally responsible for introduction of amino acid, and can manage the manufa...) (поточна)
- 12:42, 28 березня 2018 (різн. • історія) . . (+3703) . . Н The framework 3AE4 displays that the Br atom exhibiting a effectively described electron density has the identical orientation (Створена сторінка: Of all 4 syndecan genes, syndecan-4 is the only ubiquitously expressed member and features as an integrin co-receptor in mobile adhesion-promoting mitogenactiva...) (поточна)
- 14:07, 19 березня 2018 (різн. • історія) . . (+4557) . . Н Consequently our results validate final results incorporated compounds belonging to distinct structural family members (Створена сторінка: The escape box was put beneath the Focus on Gap, and the mouse was authorized to escape and relaxation in the chamber for the period of the acquisition trial. O...) (поточна)
- 10:11, 15 березня 2018 (різн. • історія) . . (+4538) . . Н Consequently our outcomes validate results integrated compounds belonging to different structural families (Створена сторінка: The escape box was positioned underneath the Target Hole, and the mouse was permitted to escape and rest in the chamber for the duration of the acquisition tria...) (поточна)
- 12:36, 14 березня 2018 (різн. • історія) . . (+4470) . . Н These families of compounds have beforehand been recognized as inhibitors of TGR and as drug hits for schistosomiasis (Створена сторінка: Liver parenchyma is surrounded by fibrillar network of collagen that is strengthened by extracellular matrix like elastin, heparin sulphate, proteoglycan, lamin...) (поточна)
- 12:28, 14 березня 2018 (різн. • історія) . . (+4189) . . Н The identification of novel drugs in certain if they target the parasite by a various system (Створена сторінка: These pathological circumstances jointly represent the second top lead to of blindness globally. Comprehending the inductive aspects and indicators that control...) (поточна)
- 10:08, 13 березня 2018 (різн. • історія) . . (+4205) . . Н We discovered a structurally diverse set of tiny scaffolds that may be overlaid onto distinct regions of the c64 ligand (Створена сторінка: In distinct, a brain imaging study showed that in contrast to healthful controls, veterans with GWI had drastically smaller sized hippocampal quantity, which co...) (поточна)
- 09:56, 13 березня 2018 (різн. • історія) . . (+4571) . . Н The Cryptosporidium parvum IMPDH crystal composition consists of inosinate and the little molecule c46 cocrystallized (Створена сторінка: The escape box was positioned underneath the Target Gap, and the mouse was authorized to escape and rest in the chamber for the period of the acquisition demo....) (поточна)
- 09:30, 12 березня 2018 (різн. • історія) . . (+4527) . . Н The Cryptosporidium parvum IMPDH crystal construction includes inosinate and the modest molecule c46 cocrystallized (Створена сторінка: The escape box was positioned beneath the Focus on Gap, and the mouse was permitted to escape and rest in the chamber for the period of the acquisition demo. On...) (поточна)
- 11:17, 9 березня 2018 (різн. • історія) . . (+4143) . . Н All compound selections ended up made from active compounds and complete dose-response info from these screens (Створена сторінка: These pathological circumstances collectively constitute the 2nd foremost trigger of blindness throughout the world. Knowing the inductive variables and alerts...) (поточна)
- 12:20, 8 березня 2018 (різн. • історія) . . (+4181) . . Н All compound alternatives ended up manufactured from energetic compounds and entire dose-response knowledge from these screens (Створена сторінка: These pathological conditions collectively constitute the second major lead to of blindness worldwide. Knowing the inductive elements and indicators that contro...) (поточна)
- 15:32, 7 березня 2018 (різн. • історія) . . (+4373) . . Н This kind of small scaffolds led to the identification of forty-three compounds between the noted TB actives (Створена сторінка: Liver parenchyma is surrounded by fibrillar community of collagen that is strengthened by extracellular matrix like elastin, heparin sulphate, proteoglycan, lam...) (поточна)
- 13:08, 6 березня 2018 (різн. • історія) . . (+4925) . . Н Nevertheless evaluation indicates that only a tiny proportion of genes are up-regulated boosts in gene expression (Nevertheless evaluation indicates that only a tiny proportion of genes are up-regulated boosts in gene expression) (поточна)
- 11:26, 2 березня 2018 (різн. • історія) . . (+5211) . . Н Silenced genes nevertheless a similar research detected only transient will increase in acetylation and extended deacetylation (Створена сторінка: Employing THP-one mobile as model cell line, listed here we present that SIRPa protein amount is downregulated by AGEs therapy, which is also correlated to an i...) (поточна)
- 11:39, 23 лютого 2018 (різн. • історія) . . (+5142) . . Н Both expansion fee were more compact in the everolimus treated teams than in other groups as noticed in other tumor models (Створена сторінка: Using THP-1 cell as model cell line, here we display that SIRPa protein amount is downregulated by AGEs treatment, which is also correlated to an increased mobi...) (поточна)
- 07:25, 14 лютого 2018 (різн. • історія) . . (+5231) . . Н For the duration of the training course of this study the crystal construction of human transketolase was produced community allowing its comparison (Створена сторінка: In maintaining with these studies, our conclusions build for the very first time a link among IRS-2 and GSK- 3b in neuronal purpose, and demonstrate that neuron...) (поточна)
- 09:00, 13 лютого 2018 (різн. • історія) . . (+5076) . . Н Appropriately sequence was utilized to configure a pharmacophore to execute a composition-based mostly digital screening (Створена сторінка: Quickly right after the addition of cells , digitonin was added, adopted by respiratory [https://en.wiktionary.org/wiki/inhibitors inhibitors] and substrates. O...) (поточна)
- 08:51, 12 лютого 2018 (різн. • історія) . . (+5199) . . Н For the duration of the program of this investigation the crystal composition of human transketolase was created community enabling its comparison (Створена сторінка: In trying to keep with these stories, our results set up for the 1st time a hyperlink among IRS-two and GSK- 3b in neuronal perform, and demonstrate that neuron...) (поточна)
- 07:07, 9 лютого 2018 (різн. • історія) . . (+5080) . . Н Accordingly sequence was used to configure a pharmacophore to execute a construction-based mostly digital screening (Створена сторінка: Right away right after the addition of cells , digitonin was included, adopted by respiratory inhibitors and substrates. Oxidative phosphorylation capacity push...) (поточна)
- 10:34, 7 лютого 2018 (різн. • історія) . . (+5242) . . Н Even so evidence for immediate binding to HCV main protein in cells has lacked so much 50 %-maximal inhibition at concentrations (Створена сторінка: In maintaining with these reviews, our conclusions create for the first time a website link amongst IRS-2 and GSK- 3b in neuronal purpose, and show that neurona...) (поточна)
- 12:32, 5 лютого 2018 (різн. • історія) . . (+14) . . м The deacetylase Sirt1 is a adverse regulator of p53 activation and Necdin interactions with this protein potentiate (поточна)
- 11:48, 2 лютого 2018 (різн. • історія) . . (+5028) . . Н The deacetylase Sirt1 is a unfavorable regulator of p53 activation and Necdin interactions with this protein potentiate (Створена сторінка: The HRPconjugated secondary antibody was diluted to 1:5000 in PBSTM one% and 50 mL aliquots ended up added to each and every nicely prior to incubating for 60 m...) (поточна)
- 11:36, 2 лютого 2018 (різн. • історія) . . (+4999) . . Н As p53 induction on genotoxic pressure is associated with several added signaling functions we directly tackled (Створена сторінка: Much more modern reports have demonstrated that [http://imgur.com/hot?q=lunasin lunasin] can inhibit the progress of some most cancers cells in tradition and in...) (поточна)
- 11:57, 31 січня 2018 (різн. • історія) . . (+5017) . . Н The deacetylase Sirt1 is a adverse regulator of p53 activation and Necdin interactions with this protein potentiate (Створена сторінка: The HRPconjugated secondary antibody was diluted to 1:5000 in PBSTM 1% and 50 mL aliquots have been additional to each nicely prior to incubating for sixty minu...)
- 11:06, 30 січня 2018 (різн. • історія) . . (+5024) . . Н Since NIH3T3 cells had been presently immortalized mainly by means of the biallelic deletion of the INK4 locus PyLT-mediated (Створена сторінка: All samples were handled with lowering agents in a reaction volume of 100 mL and incubated at space temperature for 1 hour prior to planning samples for SDS-Pag...) (поточна)
- 09:39, 25 січня 2018 (різн. • історія) . . (+5036) . . Н To even more validate the microarray knowledge Necdin expression was analyzed on an prolonged set of NIH3T3 sub-clones (Створена сторінка: All samples had been treated with decreasing brokers in a reaction volume of 100 mL and incubated at room temperature for one hour prior to planning samples for...) (поточна)
- 10:00, 24 січня 2018 (різн. • історія) . . (+5131) . . Н To additional validate the microarray information Necdin expression was analyzed on an extended established of NIH3T3 sub-clones (Створена сторінка: All samples ended up taken care of with minimizing brokers in a reaction volume of 100 mL and incubated at room temperature for one hour prior to making ready s...) (поточна)
- 09:47, 24 січня 2018 (різн. • історія) . . (+4965) . . Н These genes represented the strongest candidates with 15 upregulated and 11 downregulated genes (Створена сторінка: More current studies have shown that [https://pixabay.com/en/photos/?q=lunasin lunasin] can inhibit the development of some most cancers cells in lifestyle and...) (поточна)
- 14:10, 22 січня 2018 (різн. • історія) . . (+4966) . . Н As a preventative to hold off or avert the onset of important cognitive impairment in early phase clients (Створена сторінка: This could properly make clear the substantial losses soon after NT at this developmental stage. Cleavages have been less synchronous for NT than for ICSI embry...) (поточна)
- 12:50, 18 січня 2018 (різн. • історія) . . (+4960) . . Н As a preventative to delay or avert the onset of significant cognitive impairment in early phase clients (Створена сторінка: This may possibly nicely describe the high losses following NT at this developmental stage. Cleavages had been significantly less synchronous for NT than for IC...) (поточна)
- 13:55, 15 січня 2018 (різн. • історія) . . (+5002) . . Н Make it an superb lead compound for the development of a lot more effective inhibitors of aggregatio (Створена сторінка: As wounds in grownup utricles shut, little quantities of cells at the wound edge deform greatly. Phalloidin-labeling showed that actin belts in individuals fore...) (поточна)
- 10:23, 10 січня 2018 (різн. • історія) . . (+4941) . . Н Therefore in get to discover competitive and extremely selective inhibitors we made a decision to undertake a virtual screening (Створена сторінка: Whilst the F aspect is the most nicely-examined conjugative technique, others exist and can be dependable for the dissemination of medically critical resistance...) (поточна)
- 12:21, 8 січня 2018 (різн. • історія) . . (+6968) . . Н As a consequence of visceral illness feeding and motor activity are suppressed to the shift from carbohydrate to lipid utilization manifested (Створена сторінка: The oblique strategy averts this sort of difficulties by way of transfusion of complete blood made up of in vivo-purified 99mTc-labeled RBC from donor mice into...) (поточна)
- 11:43, 5 січня 2018 (різн. • історія) . . (+4913) . . Н The efficiency of systemic remedy to suppress brain FAS activity is however questionable in vitro (Створена сторінка: Even though the F element is the most nicely-examined conjugative program, other people exist and can be liable for the dissemination of medically critical resi...) (поточна)
- 12:35, 4 січня 2018 (різн. • історія) . . (+6523) . . Н To test this speculation we decided the effects of feeding metabolism slumber and motor activity in ghrelin receptor (Створена сторінка: In addition, genes connected to cell cycle control as effectively as cell proliferation had been also modified. The stage of cyclin D1, an essential cyclin expr...) (поточна)
- 11:48, 3 січня 2018 (різн. • історія) . . (+6926) . . Н Considering that ghrelin stimulates feeding and transgenic mice with elevated circulating ghrelin amounts have improved vitality expenditure (Створена сторінка: The oblique technique averts this sort of problems by means of transfusion of complete blood that contains in vivo-purified 99mTc-labeled RBC from donor mice in...) (поточна)
- 11:37, 3 січня 2018 (різн. • історія) . . (+5050) . . Н The solution of the preproghrelin gene enjoy a part in coordinating thermoregulatory/metabolic and snooze responses to metabolic (Створена сторінка: While the F issue is the most effectively-studied conjugative technique, other individuals exist and can be responsible for the dissemination of medically impor...) (поточна)
- 11:14, 29 грудня 2017 (різн. • історія) . . (+6568) . . Н In the in vitro experiments ORG9935 suppressed meiosis at the concentration of regular with (Створена сторінка: In addition, genes relevant to mobile cycle handle as properly as mobile proliferation have been also transformed. The level of cyclin D1, an crucial cyclin exp...) (поточна)
- 10:23, 28 грудня 2017 (різн. • історія) . . (+5290) . . Н The efficient focus of cilostazol was determined by in vitro and in vivo experiments (Створена сторінка: We could not, however, uncover any proof for p38MAPK or NF-kB activation in the current examine. The impact of oxidative tension on insulin signaling is probabl...) (поточна)
- 11:35, 27 грудня 2017 (різн. • історія) . . (+6827) . . Н PKCs are concerned in important mobile processes such as mobile proliferation apoptosis and differentiation (PKCs are concerned in important mobile processes such as mobile proliferation apoptosis and differentiation) (поточна)
- 12:49, 26 грудня 2017 (різн. • історія) . . (+6954) . . Н PKCs are involved in important cellular processes such as cell proliferation apoptosis and differentiation (Створена сторінка: The indirect method averts these kinds of issues through transfusion of total blood containing in vivo-purified 99mTc-labeled RBC from donor mice into research...) (поточна)
(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).