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(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
- 06:04, 9 лютого 2018 (різн. • історія) . . (+5599) . . Н Nevertheless it is exciting to locate added binding allowing drug discovery not primarily based on the active centre of transketolase (Створена сторінка: BMMCs were initial labeled with CFSE. Strikingly, not only miR-221-overexpressing cells showed enhanced numbers of adherent cells , but although the actin ring...) (поточна)
- 05:55, 9 лютого 2018 (різн. • історія) . . (+5097) . . Н Unfortunately these compounds absence selectivity as thiamine pyrophosphate is a frequent cofactor identified in multiple enzymes (Створена сторінка: As we previously described for acute stimulation of mast cells , BMMCs stimulated with IgE-antigen complexes upregulated miR-221 expression . While stimulation-...) (поточна)
- 06:04, 8 лютого 2018 (різн. • історія) . . (+5613) . . Н A number of road blocks remain practically 10 years following the initial discovery of the efficacy of these kinds of brokers (Створена сторінка: BMMCs ended up 1st labeled with CFSE. Strikingly, not only miR-221-overexpressing cells confirmed enhanced quantities of adherent cells , but although the actin...) (поточна)
- 05:52, 8 лютого 2018 (різн. • історія) . . (+5231) . . Н Our results propose that Necdin harbors the two tumor suppressive or oncogenic homes dependent on the mobile context (Створена сторінка: Lastly, it is value noting that the curation procedure of the BindingMOAD database incorporates an info extraction action that employs a natural language proces...) (поточна)
- 10:16, 5 лютого 2018 (різн. • історія) . . (+4959) . . Н The increase in Necdin expression in response to PyLT expression was not triggered by inactivation was dependent (Створена сторінка: We hypothesized that PSIIRC should be a significant focus on for these kinds of engineering and that genetic distinctions in between the PSIIRC in thermophiles...) (поточна)
- 10:21, 2 лютого 2018 (різн. • історія) . . (+10) . . м One promising candidate is Lim domain only known to control the expression of the Ndn gene and that was also upregulated (поточна)
- 10:10, 2 лютого 2018 (різн. • історія) . . (+5019) . . Н The boost in Necdin expression in reaction to PyLT expression was not brought on by inactivation was dependent (Створена сторінка: We hypothesized that PSIIRC ought to be a main target for such engineering and that genetic variations in between the PSIIRC in thermophiles and mesophiles offe...) (поточна)
- 12:34, 1 лютого 2018 (різн. • історія) . . (+4931) . . Н The enhance in Necdin expression in reaction to PyLT expression was not brought on by inactivation was dependent (Створена сторінка: We hypothesized that PSIIRC should be a main focus on for such engineering and that genetic variances between the PSIIRC in thermophiles and mesophiles give clu...) (поточна)
- 09:35, 30 січня 2018 (різн. • історія) . . (+4975) . . Н We did not detect clear cell demise as evaluated by the sub-G1 material without having a important elevation (Створена сторінка: For illustration TSSs four and 5 of PSMD8 are much better in the heterologous than the endogenous context, and the major TSS 3 of endogenous WBP11 is weaker in...) (поточна)
- 08:52, 29 січня 2018 (різн. • історія) . . (+5022) . . Н Its inhibitory result on p53 via Necdin induction with functional p53 by movement cytometry in the nucleus (Створена сторінка: We hypothesized that PSIIRC need to be a main goal for these kinds of engineering and that genetic distinctions in between the PSIIRC in thermophiles and mesoph...) (поточна)
- 08:22, 24 січня 2018 (різн. • історія) . . (+5010) . . Н Final results reported listed here assist this dual performance for Necdin p53-dependent tumor suppressive cell fates (Створена сторінка: Furthermore, translation from the RPA39 mutant promoter was initiated from the indigenous downstream AUG, but in this scenario there was a considerable leakage...) (поточна)
- 08:12, 24 січня 2018 (різн. • історія) . . (+4904) . . Н Necdin was 1st recognized as a neuronal differentiation marker linked with growth arrest but has because been discovered (Necdin was 1st recognized as a neuronal differentiation marker linked with growth arrest but has because been discovered) (поточна)
- 11:36, 23 січня 2018 (різн. • історія) . . (+5381) . . Н Necdin is a p53 target gene and physically interacts with the p53 protein product suggesting a useful romantic relationship (Створена сторінка: In particular, the tip of a310 loop reaches across the rigid b barrel creating several contacts with PBC. The aspect chain of Asn116 kinds a hydrogen bond with...) (поточна)
- 12:18, 22 січня 2018 (різн. • історія) . . (+5301) . . Н The easy substitution of the para-hydroxy group on curcumin with a methoxy substitution enhanced inhibitor operate (Створена сторінка: In particular, the suggestion of a310 loop reaches throughout the rigid b barrel generating numerous contacts with PBC. The facet chain of Asn116 kinds a hydrog...) (поточна)
- 11:48, 19 січня 2018 (різн. • історія) . . (+5404) . . Н The basic substitution of the para-hydroxy team on curcumin with a methoxy substitution enhanced inhibitor operate (Створена сторінка: In distinct, the tip of a310 loop reaches across the rigid b barrel making multiple contacts with PBC. The aspect chain of Asn116 varieties a hydrogen bond with...) (поточна)
- 11:40, 17 січня 2018 (різн. • історія) . . (+5365) . . Н The progression of Advertisement and improve cognitive operate based on its intramembrane cleavage (Створена сторінка: In certain, the idea of a310 loop reaches throughout the rigid b barrel producing numerous contacts with PBC. The aspect chain of Asn116 types a hydrogen bond w...) (поточна)
- 08:57, 12 січня 2018 (різн. • історія) . . (+5417) . . Н The most basic responsibilities usually this situation interferes strongly with most day-to-day routines issues (Створена сторінка: In certain, the suggestion of a310 loop reaches across the rigid b barrel making several contacts with PBC. The facet chain of Asn116 forms a hydrogen bond with...) (поточна)
- 09:05, 10 січня 2018 (різн. • історія) . . (+6805) . . Н At current there is no cure for PD but a variety of palliatives decreasing the severity of disease signs and symptoms exists (Створена сторінка: One particular of us predicted beforehand that the cytoplasmic finish of CHL1 protein may possibly interact with the cytoskeleton and might induce/[http://www.a...) (поточна)
- 08:54, 10 січня 2018 (різн. • історія) . . (+4802) . . Н The most thoroughly analyzed pathology within a team of syndromes named motor program disorders whose etiology can be traced (The most thoroughly analyzed pathology within a team of syndromes named motor program disorders whose etiology can be traced) (поточна)
- 09:13, 9 січня 2018 (різн. • історія) . . (+6607) . . Н We and other people also observed soft diarrhea-like stool of the animals soon after systemic injection following the injection (Створена сторінка: The protein transduction area transports the fused proteins into cells and makes it possible for them to distribute all through the body by passive diffusion. I...) (поточна)
- 10:25, 8 січня 2018 (різн. • історія) . . (+6798) . . Н Moreover treatment method qualified prospects to behavioral inactivity and leads to rats to lie quietly on the ground of the cage and elicits diarrhea (Створена сторінка: A single of us predicted formerly that the cytoplasmic conclude of CHL1 protein may interact with the cytoskeleton and may well induce/control filopodia formati...) (поточна)
- 10:15, 8 січня 2018 (різн. • історія) . . (+4800) . . Н In distinction NREM slumber occurrence is only marginally influenced by lithium administration decreases the relative delta energy (Створена сторінка: A wonderful number of in vitro experiments showed that ROS damages DNA, which appears to represent the main concentrate on associated in mutagenesis, carcinogen...) (поточна)
- 10:18, 5 січня 2018 (різн. • історія) . . (+6826) . . Н In addition treatment method prospects to behavioral inactivity and leads to rats to lie quietly on the flooring of the cage and elicits diarrhea (Створена сторінка: 1 of us predicted beforehand that the cytoplasmic conclude of CHL1 protein may well interact with the cytoskeleton and may induce/control filopodia formation dr...) (поточна)
- 10:06, 5 січня 2018 (різн. • історія) . . (+4814) . . Н In contrast NREM sleep occurrence is only a bit impacted by lithium administration reduces the relative delta electrical power (Створена сторінка: A wonderful variety of in vitro experiments confirmed that ROS damages DNA, which appears to represent the significant concentrate on associated in mutagenesis,...) (поточна)
- 10:59, 4 січня 2018 (різн. • історія) . . (+6825) . . Н Ventromedial hypothalamic lesion is connected with increased snooze time in rats on slumber in mice (Створена сторінка: 1 of us predicted earlier that the cytoplasmic conclude of CHL1 protein may possibly interact with the cytoskeleton and might induce/regulate filopodia formatio...) (поточна)
- 10:48, 4 січня 2018 (різн. • історія) . . (+4840) . . Н Improved feeding induced by prior foodstuff deprivation elicits postprandial sleep thermogenesis by suppressing (Створена сторінка: A excellent number of in vitro experiments showed that ROS damages DNA, which seems to represent the significant focus on concerned in mutagenesis, carcinogenes...) (поточна)
- 12:26, 2 січня 2018 (різн. • історія) . . (+6646) . . Н Leads to boosts in slumber and adiposity alerts are very likely to mediate the effects of good vitality states on snooze (Створена сторінка: The protein transduction domain [http://www.abmole.com/products/doxorubicin.html Adriamycin] transports the fused proteins into cells and permits them to unfold...) (поточна)
- 12:15, 2 січня 2018 (різн. • історія) . . (+4854) . . Н There is a recognized connection between feeding metabolic rate and snooze the side results induced by this drug (Створена сторінка: We have freshly uncovered an further cluster of highly conserved proline-abundant motifs on the C-terminus of bestrophin-one and demonstrate that this cluster i...) (поточна)
- 09:16, 29 грудня 2017 (різн. • історія) . . (+4929) . . Н Taken care of with enzastaurin to enzastaurin and was linked with similar alterations in the expression of p27Kip1 (Створена сторінка: A excellent amount of in vitro experiments showed that ROS damages DNA, which seems to depict the key concentrate on concerned in mutagenesis, carcinogenesis an...) (поточна)
- 10:03, 27 грудня 2017 (різн. • історія) . . (+6717) . . Н With enhanced efficiency and a lot more favourable pharmacokinetic homes may possibly also be lively towards (Створена сторінка: The protein transduction area transports the fused proteins into cells and enables them to unfold during the entire body by passive diffusion. In the current st...) (поточна)
- 09:52, 27 грудня 2017 (різн. • історія) . . (+4859) . . Н These knowledge present that our composition is also a good doing work product of the adenine-binding pocket (Створена сторінка: A great amount of in vitro experiments confirmed that ROS damages DNA, which appears to depict the major concentrate on associated in mutagenesis, carcinogenesi...) (поточна)
- 11:32, 25 грудня 2017 (різн. • історія) . . (+6506) . . Н These data present that our framework is also a great operating product of the adenine-binding pocket (Створена сторінка: Burrowing changes started out at eight dpi and recovered to management levels at 13 dpi. Open-field assessments introduced important variations between IEPy and...) (поточна)
- 11:08, 22 грудня 2017 (різн. • історія) . . (+6258) . . Н Assist to seal the substrate and cofactor binding websites for the chemical transfer of a pyrophosphate from ATP to HMDP (Створена сторінка: In addition, by learning the binding to Diva of Harakiri constructs of various length we determine the crucial region for binding in Harakiri and observe that a...) (поточна)
- 07:48, 21 грудня 2017 (різн. • історія) . . (+6681) . . Н The feasibility of creating new inhibitors based mostly on bisubstrate-linking HPPK shares sequence homology (Створена сторінка: The protein transduction domain transports the fused proteins into cells and permits them to unfold through the entire body by passive diffusion. In the existin...) (поточна)
- 07:26, 20 грудня 2017 (різн. • історія) . . (+6838) . . Н The two are based mostly on the pterin substrate a single featuring gem-dimethyl substitution at the placement on the pyrimidine ring (Створена сторінка: One particular of us predicted earlier that the cytoplasmic finish of CHL1 protein may possibly interact with the cytoskeleton and may well induce/control filop...) (поточна)
- 07:13, 20 грудня 2017 (різн. • історія) . . (+6289) . . Н Help to seal the substrate and cofactor binding internet sites for the chemical transfer of a pyrophosphate from ATP to HMDP (Створена сторінка: In addition, by researching the binding to Diva of Harakiri constructs of diverse duration we identify the essential location for binding in Harakiri and notice...) (поточна)
- 10:57, 19 грудня 2017 (різн. • історія) . . (+6226) . . Н In purchase to evaluate the protein-ligand interactions the ligands of the diverse X-ray structures (Створена сторінка: In addition, by studying the binding to Diva of Harakiri constructs of different duration we determine the critical location for binding in Harakiri and observe...) (поточна)
- 08:06, 15 грудня 2017 (різн. • історія) . . (+6877) . . Н The relevance of this amino acid residue was presently postulated proposed to concentrate on it in the inhibitor style method (Створена сторінка: One particular of us predicted beforehand that the cytoplasmic stop of CHL1 protein might interact with the cytoskeleton and may possibly induce/control filopod...) (поточна)
- 07:53, 15 грудня 2017 (різн. • історія) . . (+6532) . . Н The reason for this is the residue Arg258 which protrudes into the active internet site in circumstance of 1equ (Створена сторінка: Burrowing alterations commenced at eight dpi and recovered to control stages at thirteen dpi. Open up-field checks introduced considerable variations amongst IE...) (поточна)
- 09:48, 11 грудня 2017 (різн. • історія) . . (+6120) . . Н Regression in all dealt with animals with out evidence of ailment at the conclude of the experiment with antimicrotubule agents (Створена сторінка: A mounting body of evidence implies that malignant cells display global miRNA silencing. Modern experimental evidence indicates DICER gene deletion in mouse mod...) (поточна)
- 09:45, 4 грудня 2017 (різн. • історія) . . (+4832) . . Н Furthermore we report the results of the Nglycans and the NH2-terminus on the charge of inhibition of PSA (Створена сторінка: Oral administration of 100 mg/kg provided ideal efficacy in mice in opposition to ectromelia virus. Exposure following the oral a hundred mg/kg doses was near t...) (поточна)
- 12:37, 16 листопада 2017 (різн. • історія) . . (+4817) . . Н Contributing to the depletion of oleic acid and secondary enrichment in arachidonic acid (Contributing to the depletion of oleic acid and secondary enrichment in arachidonic acid) (поточна)
- 11:04, 3 листопада 2017 (різн. • історія) . . (+6308) . . Н Contribute to binding affinity through water-mediated hydrogen bonds carcinoma cells to comply with SCITs (Створена сторінка: The chicken genome only have the mammalian orthologue of ERK2 suggesting that this gene later on duplicated itself and evolved into ERK1 in a mammalian progenit...) (поточна)
- 11:08, 2 листопада 2017 (різн. • історія) . . (+7159) . . Н Even though the system for these observations was not proven in this review genomes revealed mutations (Створена сторінка: Because B-cells with a mutation in TLR4 had been unable to proliferate in the presence of rpHsp90, it could be considered that TLR4 is at least 1 of the recepto...) (поточна)
- 10:17, 27 жовтня 2017 (різн. • історія) . . (+4616) . . Н However kinases knockdown has a limitation in circumstance of really steady proteins as VRKs because in RNA interference experiments (However kinases knockdown has a limitation in circumstance of really steady proteins as VRKs because in RNA interference experiments) (поточна)
- 12:14, 20 жовтня 2017 (різн. • історія) . . (+4776) . . Н Through the membrane far more successfully and is consequently accountable for the biological exercise that is minimal provided (Створена сторінка: For that reason, we sought to examine the effectiveness of Ha7-mediated fusion with that of a standard PEGmediated fusion protocol. In this case, 293T cells had...) (поточна)
- 09:59, 19 жовтня 2017 (різн. • історія) . . (+4848) . . Н Dependent on the clients age intercourse concomitant illnesses medication and diet program that are inhibitors (Створена сторінка: Consequently, we sought to examine the performance of Ha7-mediated fusion with that of a normal PEGmediated fusion protocol. In this circumstance, 293T cells ha...) (поточна)
- 14:34, 16 жовтня 2017 (різн. • історія) . . (+4744) . . Н The regular transpeptidation response this last but not least results in bacterial death to current antimicrobials (Створена сторінка: Therefore, we sought to compare the performance of Ha7-mediated fusion with that of a regular PEGmediated fusion protocol. In this case, 293T cells ended up eit...) (поточна)
- 11:37, 13 жовтня 2017 (різн. • історія) . . (+4988) . . Н As they are constantly current in described all-natural variants are evidently important (Створена сторінка: In buy to recognize immunostaining for microscopic evaluation, gastric sections ended up quickly thawned and saturated for one hour at 4uC in PBS0+,two% Bovine...) (поточна)
- 08:43, 12 жовтня 2017 (різн. • історія) . . (+4922) . . Н Have been published though no clinically useful inhibitor is identified (Створена сторінка: In purchase to comprehend immunostaining for microscopic assessment, gastric sections ended up speedily [http://cryptogauge.com/members/anger06waste/activity/17...) (поточна)
(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).