Ch protein which includes gene entities (eg

DEPs in each on the experimental groups (OS/OB, metastasis, and chemoresistance) were in addition categorized around the basis of their biological processes working with GO10 and were designated as GO termsTechniques 2De, Istribution of quantity of mutations (in black, {increasing|growing|escalating MALDI-TOF 2De, MalDi-TOF 2D-Dige, lc-esi-Ms/Ms 2De, MalDi-TOF iTraQ labeling, lc-Ms/Ms 2De, esi-Ms/Ms 1De, lc-Ms/Ms, label-free quantitative protein analysis 2De, TOF/TOFYear 2006 2007 2009 2009 2010 2011 2013Citation Spreafico et al15 guo et al16 Folio et al17 liu et al18 Zhang et al19 hua et al22 PosthumaDeboer et al20 gemoll et alAbbreviations: OS, osteosarcoma; OB, osteoblastic; 2DE, two-dimensional gel electrophoresis; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; 2D-Dige, two-dimensional difference gel electrophoresis; iTraQ, isobaric tags for Istribution of quantity of mutations (in black, {increasing|growing|escalating relative and absolute quantitation; lc-Ms/Ms, liquid chromatographytandem mass spectrometry; ESI-MS/MS, electrospray ionization mass spectrometry; TOF/TOF, tandem time-of-flight.OncoTargets and Therapy 2017:submit your manuscript | www.dovepress.comDovepresschaiyawat et alDovepressTable three Proteomics studies of metastasis in OsModel Non-metastasis Os cell lines: hOs, saOs-2 low-metastatic subline: F4 Os tissue devoid of metastasis OB cell line: hFOB1.19 Metastasis Os metastatic sublines: 143B, lM7 hugely metastatic subline: F5M2 Os tissue with metastasized to lung Os cell lines: hs 39.T, hs 184.T, and hs 188.T a lectin column followed by MudPiT 2D-Dige, MalDi-TOF 2De, MalDi-TOF 2De, TOF/TOF 2012 2014 2014 2015 Flores et al54 chen et al55 Tang et al56 gemoll et al21 Strategies Year CitationAbbreviations: OS, osteosarcoma; MudPIT, multidimensional protein identification technologies; 2D-DIGE, two-dimensional difference gel electrophoresis; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; 2DE, two-dimensional gel electrophoresis; TOF/TOF, tandem time-of-flight.(Figure 1). DEPs in every from the experimental groups (OS/OB, metastasis, and chemoresistance) have been in addition categorized around the basis of their biological processes working with GO10 and were designated as GO termsTechniques 2De, MalDi-TOF 2De, MalDi-TOF 2D-Dige, lc-esi-Ms/Ms 2De, MalDi-TOF iTraQ labeling, lc-Ms/Ms 2De, esi-Ms/Ms 1De, lc-Ms/Ms, label-free quantitative protein analysis 2De, TOF/TOFYear 2006 2007 2009 2009 2010 2011 2013Citation Spreafico et al15 guo et al16 Folio et al17 liu et al18 Zhang et al19 hua et al22 PosthumaDeboer et al20 gemoll et alAbbreviations: OS, osteosarcoma; OB, osteoblastic; 2DE, two-dimensional gel electrophoresis; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; 2D-Dige, two-dimensional distinction gel electrophoresis; iTraQ, isobaric tags for relative and absolute quantitation; lc-Ms/Ms, liquid chromatographytandem mass spectrometry; ESI-MS/MS, electrospray ionization mass spectrometry; TOF/TOF, tandem time-of-flight.OncoTargets and Therapy 2017:submit your manuscript | www.dovepress.comDovepresschaiyawat et alDovepressTable 3 Proteomics research of metastasis in OsModel Non-metastasis Os cell lines: hOs, saOs-2 low-metastatic subline: F4 Os tissue without metastasis OB cell line: hFOB1.19 Metastasis Os metastatic sublines: 143B, lM7 very metastatic subline: F5M2 Os tissue with metastasized to lung Os cell lines: hs 39.T, hs 184.T, and hs 188.T a lectin column followed by MudPiT 2D-Dige, MalDi-TOF 2De, MalDi-TOF 2De, TOF/TOF 2012 2014 2014 2015 Flores et al54 chen et al55 Tang et al56 gemoll et al21 Procedures Year CitationAbbreviations: OS, osteosarcoma; MudPIT, multidimensional protein identification technology; 2D-DIGE, two-dimensional distinction gel electrophoresis; MALDI-TOF, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; 2DE, two-dimensional gel electrophoresis; TOF/TOF, tandem time-of-flight.(Figure 1).Ch protein including gene entities (eg, from the UniProtKB database).