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Color maps of the differences generated by superimposition allow detailed examination and quantification of the progressive dimensional changes of bone in a three-dimensional manner and enable the visualization of the apical displacement and thinning of the cortical layer of bone underneath the denture base. Most of the remodeling changes took place during the first year with a mean decrease in volume of 3.7% (SD?=?4.4%; range?=?+3.7% to ?15.9%, median?=??3.7%). This remodeling pattern continued during the second year, but at a reduced rate of 2.5% per year (SD?=?4.2%; range?=?+2.1% to ?11.3%, median?=??3.9%). Standard Tessellation Language registration based superimposition of cone beam computed check details tomography images may be considered an objective and reproducible method to three-dimensionally quantify mandibular bone remodeling. ""Objectives: This study evaluated the transference of virtual planning and planning over biomedical prototypes for dental implant placement using guided surgery. Material and methods: This experiment was conducted with 11 identical replicas of a human edentulous mandible. For each mandible, models and surgical guides were manufactured using stereolithography. Simulated GDC-0973 datasheet surgeries were performed on the prototypes. Following this, the implants were placed in the mandible replicas. Superposition of the tridimensional pre- and postoperative models was used for virtual evaluation. The real evaluation was conducted by linear measurements directly on the models. Results: The variations in angles and distances between the coronal, central and apical regions of the 22 implants Aldosterone evaluated in this study had mean values