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The main characteristics of the responding population are summarized in Table?1, and data on immunization status are shown in Table?2. Regarding diseases frequently involved in nosocomial epidemics, 81 residents (32.4%) had a past history of measles during childhood, and 157 (62.8%) reported having received at least one dose of measles vaccine (34 received two shots). Nevertheless, 60 residents (24%) without a past history of measles were not vaccinated. Regarding influenza vaccination, 114 (45.6%) had been vaccinated during the past year and 164 (65.6%) the year before. The majority of residents were vaccinated at their site of work: 63 (55.3%) at occupational medicine departments, and 39 (34.2%) in their S6 Kinase unit. Five (4.4%) reported self-vaccination and seven (6.1%) received vaccination from their treating physician. Reasons for vaccination or non-vaccination are detailed in Table?3. Importantly, 201 (80.4%) declared that they were willing to receive vaccination for the next influenza season, LY294002 and 185 (74%) recommended vaccination to their relatives. Regarding severe diseases sometime contracted by the healthcare workers, all responders reported previous vaccination against HBV, and 198 (79.2%) had previously controlled their anti-HBs antibody titers. Four residents (1.6%) were uncertain of their vaccination status against tuberculosis. Regarding other vaccinations, all but eight residents (3.2%) were up to date for dTP (last booster dose Protein Tyrosine Kinase inhibitor (86%) reported a history of varicella during childhood. Of the 35 remaining residents, 22 (62.9%) had been vaccinated and 12 (34.3%) had controlled their serology. Eighty-four residents (33.6%) reported having been in charge of patients at high risk of severe varicella infection. Finally, immunization coverage for other vaccines was as follows: typhoid fever, 116 residents (46.4%); hepatitis A virus, 124 (49.6%); yellow fever, 74 (29.6); meningococcus, 35 (14%). To date, very few studies have addressed the question of vaccination coverage in medical residents, with the most studied issue being influenza vaccination [5�C8]. A low vaccination coverage against influenza has been previously reported in medical residents [2,9], although this coverage is higher than in other healthcare workers [2]. In the present survey, the main reason for non-vaccination against influenza was the lack of time, in contrast to previous studies reporting the perception of a low risk of contracting influenza as the most common reason for vaccine refusal [9]. Over a 2-year period, we found vaccination coverage of 45.6% and 65.