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The homicide (n?=?20) and non-homicide (n?=?135) offender groups did not differ in age (t(153)?=?0.28, p?=?.776, IQ, t(146)?=?0.04, Mdm2 antagonist p?=?.965) or socioeconomic status (t(137)?=?1.02, p?=?.307; Table 1). The homicide offenders did, unsurprisingly, score higher on CU/CD traits than did non-homicide offenders, including both interpersonal and affective traits and lifestyle and antisocial traits ( Table 1; Psychopathy Checklist: Youth Version (PCL:YV) total scores: t(153)?=?4.26, p?find more non-homicide offenders. The comparison between homicide offenders (n?=?20) and non-homicide offenders (n?=?135) showed vast differences in gray matter throughout the majority of the brain, due to significant differences in both overall brain volume and gray matter (Supplementary Fig. S1). Inline Supplementary Org 27569 Figure S1 Fig.?S1.? Homicide offenders (n?=?20) vs. non-homicide offenders (n?=?135) without covariates. Regional gray matter volume decreases in homicide offenders (n?=?20) compared with non-homicide offenders (n?=?135). All voxels indicated in blue color map represent regions that are significant after correcting for searching the entire brain using a cluster-corrected threshold of p?