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The measures are reported in Table 3. In addition to simple t-tests, the repeated measures data was analysed using a generalized estimating equations approach to fit the nature of proportion data. Infant first look behaviour within each of the two sets of trials (7-month and 14-month) was analysed as binomial proportions and logistic link function with robust standard errors to account for overdispersion and correlation between 7- and 14-month assessments. For the remaining measures, formed as averages over each segment of trials, of times, counts and their [http://www.selleckchem.com/products/BKM-120.html NVP-BKM120 clinical trial] ratios, a Gaussian error, identity link, and an unstructured correlation matrix were used. Group differences were assessed from Wald tests with a parameter covariance matrix (and thus test statistics) calculated accounting for the number of parameters estimated. This approach is equivalent to multiple analysis of variance. Due to the variation of age within each group at the 7- and 14-months assessments stage, in all analyses the infant's age at was included as a covariate. The proportion of valid trials in which the infant looked towards the face AOI before any other AOI was calculated for each group at each age (Table 2). One sample t-tests showed that [http://www.selleckchem.com/products/BIBW2992.html BIBW2992 molecular weight] the proportion of trials with first looks towards the face was significantly above chance level (.2) at 7-months for all groups defined based on risk status (control vs. at-risk) or on outcomes (at-risk: ASD, typical, other; all p?[http://en.wikipedia.org/wiki/SWAP70 SWAP70] significant mean differences among the groups (group ��2(1)?=?2.83, p?=?.092). The average amount of looking anywhere in the array is shown in Table 3. A model was constructed with the following terms: between subjects groups (control, at-risk), and within-participants time (7-months vs. 14-months) and trial segment (first 5?s vs. last 10?s). In addition, age in months at the two points of measurement was used as a covariate. For the average time per trial examining AOIs the repeated measures analyses indicated no significant interactions involving group: group?��?time?��?segment (��2(1)?=?0?48, p?=?.490), group?��?segment (��2(1)?=?0?38, p?=?.535), group?��?time (��2(1)?=?1?79, p?=?.181). For visual foraging, i.e., AOI count, the 3-way interaction of group?��?age?��?segment was not significant (��2(1)?=?0.06, p?=?.803) nor were the 2-way group?��?segment (��2(1)?=?0.06, p?=?.81) interactions but the group?��?time was marginal (��2(1)?=?3.28, p?=?.070) as was the group main effect (��2(1)?=?3.82, p?=?.