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5?mg/kg) IV to keep the same proposed plane of anesthesia. Continuous physiological parameters evaluated are shown in Table?2. It was not possible to evaluate arterial blood pressure in all animals due to the small size of the animals and poor muscle relaxation in TZ. No significant differences were found in heart rate and temperature, and there were minor differences between groups in the other parameters. RR was lower in PRO during all the procedures, but significantly inferior from the 40�� assessment to the end (P? from the 20�� assessment and in TZ from the 30�� assessment in relation to the beginning of anesthesia (P?check details and increases in PaCO2 and PaO2. Low values of bicarbonate were observed, as well as negative base excess. Ionized calcium, total serum calcium, potassium, and sodium were statistically different between groups, being higher in TZ (P?Antiinfection Compound Library datasheet In both groups, some animals presented an increase and others a decrease in cortisol levels when compared to the initial value (moment 0��). The variation in PRO ranged from ?18.66% to 56.65%, presenting a mean increase of 24.43?��?38.84% and in TZ it ranged from ?66.43% to 134.99%, with a mean increase of 17.18?��?84.88%. The anesthesia recovery evaluation is shown in Table?4. There was no statistical difference in time for first voluntary movements or posture repositioning. However, times for postural recovery, hanging, and normal ambulation ATP7A were significantly shorter in PRO (P?