Lls was TA (58 ), and for GB cells was NTA (46 ) (Figures 5, 6C

IMB cells contacted only M/L-cones and BB cells contacted only S-cones. Thus, the M/L-cone-IMB pathway along with the S-cone-BB pathway appear structurally independent. Other DB and GB cells practically exclusively contacted M/L-cones and only rarely contacted Scones. Only certainly one of six DB4 cells connected to a single S-cone with one make contact with, two of 7 DB5 cells connected to two S-cones with one speak to and two contacts, respectively, two of 5 DB6 cells connected to two S-cones each with one get in touch with, and certainly one of two GB cells connected to one S-cone with two contacts. Thus, the mean variety of contacts with S-cones per bipolar cell (Table 1) was at most a single. In addition, these S-cone contacts with DB and GB cells were normally positioned at non-invaginating positions (TA or NTA).Frontiers in Neuroanatomy | www.frontiersin.orgOctober 2016 | Tacts with ON PG cells and OFF DB cells with OFF Volume 10 | ArticleTsukamoto and OmiMacaque ON Bipolar Cell ConnectivityFIGURE 3 | ON-OFF lateral amacrine cell in get in touch with with DB2 and DB4 cells. Distribution of your postsynaptic web-sites with the ON-OFF lateral amacrine cell in speak to together with the ribbon-associated presynaptic internet sites of DB2 and DB4 cells is displayed in top rated view (A) and side view (B). The cellular contours are shown with continuous lines for innervated cones and dotted lines for non-innervated cones. M/L-cone contours are colored gray and S-cone contours blue.In Figure five, 12 M/L-cones and six S-cones shown in gray have been utilized for evaluation of cone divergence, determined by identifying all companion bipolar cells with each other with all the number of output title= 2042098614560730 synaptic contacts. We investigated all ON bipolar dendrites surrounding these target cones. The divergence patterns differed significantly among M/L- and S-cones (Table 2, Figures 6D,E). The M/L-cone directed virtually half of all output synapses (26) to IMB cells and allocated the other half to four non-IMB cells in decreasing order DB4 (14) > DB5 (ten) > DB6 (two) > GB (0.5). In contrast, the S-cones directed pretty much all outputs (40) title= s12936-015-0787-z to BB cells and sporadically title= acr.22433 allocated the handful of remaining contacts (1) to 4 other ON bipolar types. Thus, the mean number of DB and GBcells per S-cone and also the mean quantity of contacts innervating on these DB or GB cells per S-cone have been each at most 0.5 (Table 2). Figure 6F shows the divergence of output in the representative M/L-cone and S-cone to their ON and OFF routes via 3 positional classes of contacts. M/L-cone pedicle P41 had 32 ribbons, and S-cone p.Lls was TA (58 ), and for GB cells was NTA (46 ) (Figures five, 6C). These distinct ON bipolar cells also displayed distinct connectivity patterns to M/L- and S-cones, suggesting typespecific variations in chromaticity. IMB cells contacted only M/L-cones and BB cells contacted only S-cones. As a result, the M/L-cone-IMB pathway and the S-cone-BB pathway seem structurally independent.