My Spanking New Sitaxentan Software Work While You Go To Sleep! !

Pediatr Pulmonol. 2010; 45:197�C201. ?2009 Wiley-Liss, Inc. ""Division of Pulmonology, Department of Pediatrics, University of Wisconsin. Lung function (FEV1) generally improves during treatment of pulmonary exacerbations in patients with cystic fibrosis (CF). However, it is unclear how often return to previous baseline FEV1 is achieved. (1) To determine the proportion of pediatric patients with CF treated for a pulmonary exacerbation who fail to recover to baseline Forskolin FEV1 and (2) to identify factors associated with this failure. We performed a case�Ccontrol analysis of patients from a single pediatric CF center admitted for their first pulmonary exacerbation in 2001�C2006. Patients were considered to have recovered to baseline FEV1 if their best FEV1 within the 3 months following treatment was ��95% of the best FEV1 during the 6 months prior to treatment. Logistic regression was used to estimate associations between clinical characteristics and failure to regain baseline FEV1. Of 104 patients, 24 (23.1%) did not recover to baseline FEV1. The adjusted odds ratio of failure to recover to baseline FEV1 was 1.49 (95% confidence interval [CI] 1.20, 1.86) for every 5% greater decline in FEV1 from baseline to admission. In exploratory Sitaxentan analyses, the adjusted odds ratios for the failure to recover to baseline were also significantly higher for patients who were evaluated in our CF clinic more frequently between the baseline measurement and admission, were younger, or were insured by Medicaid. Approximately one in four patients with CF failed to recover to baseline lung function after a pulmonary exacerbation despite treatment with intravenous antibiotics. Failure to recover to baseline was associated with the degree of decline in FEV1 that had occurred prior to hospital admission, CX-5461 in vitro suggesting opportunities for earlier intervention to improve lung function outcomes. Additional studies are needed to determine how the failure to recover to baseline affects subsequent FEV1 decline. Pediatr Pulmonol. 2010; 45:127�C134. ? 2010 Wiley-Liss, Inc. ""Children of parents who perceive their children have increased asthma severity use more medical services and reliever medication. A randomized control trial of the Roaring Adventures of Puff (RAP) education program was completed among 287 grade 2�C5 children with asthma. Parents and children completed a quality of life (QOL) questionnaire pre-intervention, 6 and 12 months post-intervention. We hypothesized that RAP altered how parent's assessed their child's QOL with a resultant change in asthma management. Pre-intervention, parents rated their child's overall QOL higher than their child (parent 5.41 [95% CI 5.24, 5.58] vs. child 4.54 [95% CI 4.32, 4.75]; P?