Our Two-Second Measure Over RhoC

01). The highest incidence of seroma and largest aspirated volumes were found in RhoC patients with short-term drainage and MRM. No difference in incidence of wound infection was found between both groups, and overall incidence of wound infection was 32%. Seroma formation itself was associated with a higher risk of wound infection (OR 4.39 95% CI 1.6�C12.1). Short-term axillary drainage does not lead to an increase in wound-related problems, but is associated with a higher incidence of seroma. This seems especially the case in patients who underwent MRM. Therefore, we propose a differentiated policy: patients treated with MRM should be offered long-term axillary drainage, whereas patients treated with breast conserving therapy and ALND or completing ALND after a positive sentinel node should be offered short-term axillary drainage. ""Abstract:? Lymphedema (LE) is a well-known postoperative complication after axillary node dissection (ALND). Although, sentinel lymph node dissection (SLND) involves more focused surgery and less disruption of the axilla, early reports show up to 13% of patients experience some symptoms of LE. The purpose of this study was to determine predictors of arm LE in our patients under going SLND with or without an ALND. One hundred and thirty-seven breast cancer patients were treated at a comprehensive cancer center. Prospective measurement of arm volume was carried every 6?months from date of diagnosis. This data base was retrospectively reviewed for tumor stage, treatment, and subjective complaints Apoptosis inhibitor of LE. Objective LE was defined as a change greater than 200?mL compared with the control arm. Univariate and multivariate analyses were performed. Arm volume changes were measured over 24?months (median follow-up 20?months) in Selleckchem Galunisertib 137 women: 82 stage I, 48 stage II, and 5 stage III; median age 56?years. Breast-conserving surgery was performed in 133 patients. All patients underwent SLND for axillary staging and for 52 patients this was the only axillary staging procedure. All node-positive patients (31) and 54 node-negative patients under went an immediate completion ALND, the latter as part of a study protocol. At 24?months, 16 (11.6%) patients were found to have objective LE (>200?mL increase). Patient age, tumor size, number of nodes harvested, or adjuvant chemotherapy was not found to be predictive of LE by univariate analysis. The risk of developing postoperative LE was primarily and significantly related to the patients�� BMI (p?=?0.003). Multivariate analysis revealed patients with a BMI >30 (obese) had an odds ratio of 2.93 (95% CI 1.03�C8.31) compared with those with a BMI of