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Версія від 12:21, 16 червня 2017, створена Bumper0hook (обговореннявнесок) (Створена сторінка: ""Study Objective. To evaluate the influence of distress on overall survival of patients with hematologic malignancies who underwent allogeneic stem cell transp...)

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""Study Objective. To evaluate the influence of distress on overall survival of patients with hematologic malignancies who underwent allogeneic stem cell transplantation (allo-SCT) and to analyze the possible risk factors for death. Design. Retrospective cohort study. Setting. Large tertiary care teaching hospital. Patients. Seventy-seven patients (aged �� 15 yrs) with hematologic malignancies who underwent allo-SCT between January 2000 and August 2007; 20 patients with distress history were matched in a 1:3 ratio with 57 patients without distress history. Measurements and Main Results. The primary outcome was overall survival, defined as the time from allo-SCT to disease-related death or last date of follow-up. Secondary outcomes were time to Ritonavir hematologic recovery (absolute find more neutrophil count �� 500 cells/mm3) from day of allo-SCT, length of hospital stay, and opioid usage. Sociodemographic information and clinical characteristics were analyzed for possible risk factors. Patient history of psychological distress resulted in a significantly higher mortality rate in the first year after allo-SCT (hazard ratio [HR] 3.05, 95% confidence interval [CI] 1.48�C6.28, p=0.001) and led to a shorter overall survival rate (HR 1.63, 95% CI 0.86�C3.10, p=0.133). However, psychological distress had no effect on hospital length of stay, hematologic recovery time, opioid usage status, or dose of opioid analgesics used. Factors associated with death after allo-SCT in the univariate analysis (pSCH772984 solubility dmso (C-G Clcr) equation compared with measured 24-hour Clcr. Retrospective analysis. Tertiary care hospital. A total of 3678 patients with stable renal function and who underwent a 24-hour urine collection between July 1, 1996, and June 30, 2010. For each patient, C-G Clcr was calculated and compared with a measured 24-hour Clcr. Body weight adjustments to the calculation were performed based on the following weight classifications: underweight, normal weight, overweight, obese, and morbidly obese. In addition, C-G Clcr was calculated by using rounded Scr values based on two Scr thresholds��0.8 ?mg/dl and 1?mg/dl��for patients with measured Scr values below those thresholds.