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We also excluded studies that assessed adherence to Mediterranean diet subjectively without the use of a score, those with case control design, and those that analyzed adherence to a non-specific dietary pattern rather than a Mediterranean diet. Our initial search yielded 72 articles, of which 25 were excluded on the basis of abstract. Exclusion of the abstracts was based on the content and its relevance to our review, and whether it fits our inclusion/exclusion criteria. binedaline Most of the abstracts reviewed had full text available. Of the remaining 47 articles, 23 articles were excluded for either not having diabetic patients in the study population, or for being a case-control design, or having evaluated a non-specific dietary pattern rather than Mediterranean diet, or having short follow up period (Talazoparib clinical trial sensitivity in T2DM patients when compared to control diets (low-fat diet/usual dietary habits). Table 1 List of randomized studies on effect of Mediterranean selleckchem diet on fasting glucose and HbA1c. Mediterranean diet effect on plasma glucose and HbA1c There has been good evidence that adherence to Mediterranean diet might have a beneficial role in glycemic control. In fact, Esposito et al. conducted a cross-sectional analysis of a population of 901 diabetic outpatients attending diabetes clinic in south Italy. In this study, adherence to Mediterranean diet was inversely associated with both postprandial glucose levels and HbA1c. In multivariate analysis, mean HbA1c and 2-h post-meal glucose concentrations were significantly lower in diabetic patients with high adherence to a Mediterranean-type diet (adherence score 6�C9) compared to those with low adherence [difference: HbA1c 0.9%, 95% confidence intervals (CI) 0.5�C1.2%, P?