Transcription elements potentially stabilize inter-chromosomal contacts irrespective from the influence of

5b): clusters enriched using the TFs in the IRTF-dominated Group 2 are located most centrally in the nucleus; clusters enriched with all the TFs from the activator-dominated Group 3 have a tendency to be located amongst the nuclear centre plus the periphery; and clusters withNATURE COMMUNICATIONS | 7:11549 | DOI: ten.1038/ncomms11549 | www.nature.com/naturecommunicationsNATURE COMMUNICATIONS | DOI: ten.1038/ncommsARTICLEcaDomain occurrence100 0 500bFraction of centromeric domains in clustersXDomain occurrence in Sment Checklist for Seniors with Restricted Ability to Communicate ?Portuguese em interchromosomal clusters0.16 17 18 190.0.dChromosome armChromosome armActive domain proportionCluster radial positionCluster frequency1,000 800 600 4001 two ss ssCluster gene density1.0 0.eight 0.six 0.four 0.2 0.1 two ss ss la laCluster gene expressionCentromere domainsNuclear envelope1 ss la C C lasssssslalalalalaCCCCCCCCentromeric influenceCentromeric influenceCentromeric influenceCentromeric influenceClassCentromeric influencefCentromere distance four,000 three,000 two,000 1,P valuejir.2014.0026 as the circular plot, where centromeric srep39151 domains are coloured as yellow, active domains are coloured as red and inactive/other domains are coloured as grey. (b) A plot measuring the correlation amongst linear centromeric distance and domain occurrence in inter-chromosomal clusters. Data are shown as imply .d. on the mean.