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Adherence to ACG/AGA/ASGE guidelines, which support the administration of sedation by non-anesthesia providers to average-risk patients receiving a screening colonoscopy, was measured.14 Statistical analysis Descriptive statistics were produced for each set of the study measures. Mean and reported standard deviation for continuous variables, and frequency counts and percentage UNC2881 for categorical variables, were reported. McNemar��s test was used to determine the statistical significance of differences in categorical measures, including comparison of the ratings based on RCRI score and ASA status. The study cohorts for evaluating the impact of an anesthesia provider were obtained by matching patients who had an anesthesia provider on the index date with those without an anesthesia provider, using the propensity score method on a 1:1 basis.15 The Parsons algorithm selected matched pairs and the final cohorts, using the five digits match.16 Logistic regression using the generalized estimating equations (GEE) method was used to incorporate the matched pairs design and compare the effects of having an anesthesia provider present on the efficacy of colonoscopy in identifying colon cancer; the completion of the colonoscopy on the index date (as defined by coding that the examination was completed distal to the splenic flexure); the requirement for a repeat colonoscopy within 6 AP24534 chemical structure months; the development of an MI (a new primary ICD-9 code for the hospital encounter) within 7 days of colonoscopy; the incidence of stroke (a new primary ICD-9 code for the hospital encounter) within 7 days of colonoscopy; and the incidence of a hospital admission within 7 days of the screening colonoscopy in both groups. SAS (v.9.1; SAS Institute Inc., Cary, NC, USA) was used for all statistical analyses. Results Baseline characteristics Table 1 reports the demographics and the frequency of comorbid conditions among the patients who received screening colonoscopies. Inclusion criteria were met by 63,750 Humana members. http://www.selleckchem.com/products/Imatinib-Mesylate.html Only 6.52% of subjects had an ASA score submitted, of which the most commonly reported score was a physician status 3. The majority of patients had 0 or 1 RCRI factors (73% and 19%, respectively). An anesthesia provider was present in 25.48% of screening colonoscopies. Table 1 Baseline demographic and clinical characteristics in whole population Provider type, outcomes, and adverse events High-risk patients were significantly more prevalent among the group having an anesthesia provider present during the colonoscopy (9.3% vs 7.5%, P