Way Too Hectic To Manage A-1210477?

7%) were girls. The mean age was 13.74��2.49, ranging from 10-18 years. Weight, weight SDS, height, height SDS, BMI, WC, SBP, fasting glucose, HDL cholesterol, and QUICKI differed significantly between the sexes. The serum 25(OH)D concentration and prevalence of metabolic syndrome were significantly higher in boys than in girls. The mean serum 25(OH)D concentration of all participants Selleckchem A 1210477 was 17.42��8.95 ng/mL (Table 1). Table 1 Basic characteristics of the study subjects All subjects were divided into four groups according to quartiles of serum 25(OH)D concentration, namely I (LDN-193189 research buy data (Table 2). Table 2 Factors of metabolic syndrome, anthropometric indices, and insulin sensitivity index according to quartiles of serum 25(OH)D concentration When vitamin D deficiency was defined as less than 20 ng/mL19), most of subjects were vitamin D deficiency except IV quartile group. We put together subjects from first quartile group to third quartile group and performed analysis of comparison with IV quartile group. There were significant difference in mean age, SBP, DBP, WC, fasting glucose, BMI, weight, height, HOMA-IR and QUICKI between two groups. The occurrence of metabolic syndrome was significantly lower in IV quartile group (P=0.029) (Table 3). Table 3 Comparison of factors of metabolic syndrome, anthropometric indices, and insulin sensitivity index between serum 25(OH)D quartile I-III groups and quartile IV group Finally, the association between serum 25(OH)D level and insulin sensitivity index is presented in Table 4. Partial correlation analysis revealed an inverse correlation between serum 25(OH)D and HOMA-IR (��=-0.073) and a positive correlation between serum 25(OH)D and QUICKI (��=0.095). Table 4 Partial correlation between serum 25(OH)D and insulin sensitivity index Discussion In this study, we analyzed the relationship between serum 25(OH)D levels and risk factors for metabolic syndrome in Korean children and adolescents using nationally representative data collected for 3 years. We tried to show the correlation of serum 25(OH)D with not only metabolic component, but also insulin sensitivity index. diglyceride Our study found low serum 25(OH) D concentrations were related with elevated blood pressure, abdominal obesity, increase of insulin resistance, and high prevalence of metabolic syndrome. Several studies have investigated the relationship between serum 25(OH)D levels and cardiovascular risk factors, such as insulin resistance and abdominal obesity. In a study of 1,660 nine-year old Korean children, Lee et al.20) found that vitamin D deficiency in children may be a risk factor for obesity and metabolic syndrome. Reis et al.