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- In our model the neutral BZB translocates assisted by a water channel bound
- In our model the neutral BZB translocates assisted by a water channel bound to the boronic group
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- In particular, G4 ligand treatment of telomerase-positive glioma cell lines resulted in telomere instability, cell cycle alterations and apoptosis in a telomere lengthindependent manner
- In particular the damaging sort passes throughout bacterial membranes is still a matter of debate
- In patients with sophisticated non-small cell lung cancer
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- In response to HDACi and that as many are down-controlled as activated even following brief durations of inhibitor therapy
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- In settlement with these results enzastaurin drastically lowered BrdU incorporation in mutant mobile lines
- In situ hybridrization for the Hedgehog ligand, Ihh, demonstrating that GSK-3b 2/2 embryos have decreased Ihh transcripts in the palatine bone when compared to controls
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- In spite of this significantly decreased affinity for cognate ligand, 2D2 T cells effectively proliferated and produced cytokines
- In spite of this significantly decreased affinity for cognate ligand, 2D2 T cells successfully proliferated and developed cytokines
- In sufferers with sophisticated non-small cell lung cancer
- In sum, the results indicate that precise positioning and spacing of the recruited target protein as it is bound to the F-box domain does not appear to significantly influence the availability of the target protein as a substrate for the E3-ligase
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- In target positions, including the renal proximal tubule or perhaps a