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(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).
- 12:37, 26 грудня 2017 (різн. • історія) . . (+5218) . . Н The PKC family members is a broadly expressed team of serine/threonine kinases comprising at the very least twelve isoforms (Створена сторінка: We could not, nonetheless, locate any proof for p38MAPK or NF-kB activation in the current examine. The affect of oxidative pressure on insulin signaling is ver...) (поточна)
- 13:19, 25 грудня 2017 (різн. • історія) . . (+6602) . . Н PKCs may enjoy crucial roles in tumor development and progression invasiveness of cancer cells and chemoresistance (Створена сторінка: In addition, genes connected to mobile cycle management as well as cell proliferation have been also transformed. The degree of cyclin D1, an crucial cyclin exp...) (поточна)
- 13:07, 25 грудня 2017 (різн. • історія) . . (+6158) . . Н The gene encodes for the a subunit of course of heterotrimeric GTP binding protein mediates signals (Створена сторінка: Utilizing the N1E-one hundred fifteen neurite proteome as a template, a combination of genetic perturbations and substantial resolution dwell mobile imaging met...) (поточна)
- 13:25, 22 грудня 2017 (різн. • історія) . . (+6052) . . Н In line with the higher pterin-site specificity is the large ligand efficiency of 8-mercaptoguanine (Створена сторінка: Making use of the N1E-one hundred fifteen neurite proteome as a template, a mixture of genetic perturbations and substantial resolution dwell cell imaging strat...) (поточна)
- 09:28, 20 грудня 2017 (різн. • історія) . . (+6889) . . Н Apparently by co-crystallisation which may possibly open the probability for a multi goal inhibitor derived (Створена сторінка: The oblique strategy averts such troubles by means of transfusion of total blood made up of in vivo-purified 99mTc-labeled RBC from donor mice into review mice....) (поточна)
- 09:18, 20 грудня 2017 (різн. • історія) . . (+6348) . . Н Despite these scientific studies no antibacterial activity has been documented beforehand from this scaffold (Створена сторінка: The deficiency of noticed changes in physiology noted herein might replicate reduced murine VEGF amounts in healthy tissues relative to tumors in mice. Without...) (поточна)
- 11:58, 14 грудня 2017 (різн. • історія) . . (+6823) . . Н For that reason we targeted on the discovery of compounds with no low affinities to the ERs with out regarding agonistic (Створена сторінка: The indirect approach averts these kinds of troubles through transfusion of total blood that contains in vivo-purified 99mTc-labeled RBC from donor mice into re...) (поточна)
- 11:45, 14 грудня 2017 (різн. • історія) . . (+6324) . . Н An antagonistic method of motion on the other hand will direct to systemic outcomes in other wholesome steroidogenic tissues (Створена сторінка: The absence of noticed modifications in physiology reported herein may possibly mirror reduce murine VEGF stages in healthful tissues relative to tumors in mice...) (поточна)
- 12:04, 11 грудня 2017 (різн. • історія) . . (+5927) . . Н In buy not to counteract the therapeutic efficacy of 17b-HSD1 inhibitors it is essential the compounds are selective (Створена сторінка: In clients, infusion of allogeneic hMSCs has been demonstrated to mitigate acute graft-compared to-host ailment to different levels. The status âânon-...) (поточна)
- 11:59, 7 грудня 2017 (різн. • історія) . . (+7304) . . Н By a various p53 gene status supports the implication of modulation of wild-sort p53 in mediating (Створена сторінка: Considering that the physical appearance of extremely energetic antiretroviral treatment options the [http://www.abmole.com/products/nutlin-3.html Nutlin-3] met...) (поточна)
- 11:22, 7 грудня 2017 (різн. • історія) . . (+5887) . . Н Similar results had been observed by combining ST2782 with the microtubule depolymerising agent vinorelbine (Створена сторінка: In individuals, infusion of allogeneic hMSCs has been proven to mitigate acute graft-versus-host illness to numerous degrees. The track record âânon-i...) (поточна)
- 13:54, 6 грудня 2017 (різн. • історія) . . (+7159) . . Н By a various p53 gene standing supports the implication of modulation of wild-kind p53 in mediating (Створена сторінка: Considering that the visual appeal of highly lively antiretroviral therapies the process of HIV/AIDS becoming a continual ailment in the industrialised globe ha...) (поточна)
- 13:15, 5 грудня 2017 (різн. • історія) . . (+5739) . . Н This conclusion and demonstrates that the N-glycosylation of PCI shows a extremely tissue-specific expression (Створена сторінка: Below we display that E4orf1 is needed to mediate the glucose uptake induced by Ad36. Also, E4orf1 is sufficient to promote glucose uptake in preadipocytes, adi...) (поточна)
- 09:42, 5 грудня 2017 (різн. • історія) . . (+3) . . м In neither blood nor seminal plasma PCI N-glycans the kidney is a source for urinary PCI (поточна)
- 14:21, 4 грудня 2017 (різн. • історія) . . (+5665) . . Н This summary and demonstrates that the N-glycosylation of PCI displays a highly tissue-particular expression (Створена сторінка: Here we demonstrate that E4orf1 is needed to mediate the glucose uptake induced by Ad36. Also, E4orf1 is sufficient to market glucose uptake in preadipocytes, a...) (поточна)
- 14:02, 22 листопада 2017 (різн. • історія) . . (+5523) . . Н Glucagon-like peptide-1 is an incretin hormone secreted by the little intestine in response to nutrient ingestion (Glucagon-like peptide-1 is an incretin hormone secreted by the little intestine in response to nutrient ingestion) (поточна)
- 14:30, 3 листопада 2017 (різн. • історія) . . (+6808) . . Н Nevertheless some PKC inhibitors do not stop the suppression of the M-existing induced by muscarinic agonists (Nevertheless some PKC inhibitors do not stop the suppression of the M-existing induced by muscarinic agonists) (поточна)
- 13:41, 3 листопада 2017 (різн. • історія) . . (+6069) . . Н Aid composition dependent development of certain inhibitors led to an exclusion of PKC (Створена сторінка: In summary, this review of MinE illustrates the common mechanisms included in the concentrating on of peripheral membrane proteins that are able of leading to m...) (поточна)
- 14:50, 2 листопада 2017 (різн. • історія) . . (+6524) . . Н One particular case in point is the acetylcholine induced suppression of the M-type potassium channel exhibited a lessen in potency (Створена сторінка: This consequence was supported by Charhour et al. in a review displaying the conversation of MeCP2 with the transcriptional activator CREB1 at energetic promote...) (поточна)
- 14:17, 20 жовтня 2017 (різн. • історія) . . (+4721) . . Н In our model the neutral BZB translocates assisted by a h2o channel sure to the boronic group (In our model the neutral BZB translocates assisted by a h2o channel sure to the boronic group) (поточна)
- 14:05, 20 жовтня 2017 (різн. • історія) . . (+5058) . . Н Our experiments build that BZB passes via the membrane equally in charged and neutral form (Створена сторінка: For all experiments, each and every sample signifies the brain of a one mouse. Differentially expressed gene sets had been compared to Gene Ontology organic pro...) (поточна)
- 12:00, 19 жовтня 2017 (різн. • історія) . . (+4821) . . Н Experiments with reconstituted membranes were carried out making use of BZB and BZD for comparison (Створена сторінка: Furthermore, proximity ligation assay verified the particular conversation between CXCR4 on leukemic cells and SDF1 . As a result, these results strongly recomm...) (поточна)
- 12:37, 18 жовтня 2017 (різн. • історія) . . (+4896) . . Н Experimental screening for the estimation of antithrombin and anticoagulant actions of the compounds (Створена сторінка: To determine mutation-induced alterations in general gene expression in the mouse mind, we done total genome microarray analyses at diverse time details [http:/...) (поточна)
- 12:03, 17 жовтня 2017 (різн. • історія) . . (+4805) . . Н It was subsequently revealed that APH-IIIa can be inhibited by protein kinase inhibitors of the isoquinolinesulfonamide family members (Створена сторінка: Moreover, proximity ligation assay verified the specific conversation between CXCR4 on leukemic cells and SDF1 . Consequently, these benefits strongly recommend...) (поточна)
- 16:30, 16 жовтня 2017 (різн. • історія) . . (+4651) . . Н The investigation of APH inhibitors that concentrate on the ATP-binding pocket was facilitated by the structural similarities (Створена сторінка: Nonetheless, the identification of the orthologs of MAPK4 or MAPK6 in Ciona intestinalis suggests that the origin of the MAPKs four&six subfamilies should have...) (поточна)
- 16:18, 16 жовтня 2017 (різн. • історія) . . (+4844) . . Н For aminoglycosides a group of antibiotics utilized to handle critical nosocomial bacterial infections the principal mechanism of resistance (Створена сторінка: To discover mutation-induced adjustments in general gene [http://www.abmole.com/products/mk-2206.html inquiry] expression in the mouse mind, we carried out enti...) (поточна)
- 14:27, 13 жовтня 2017 (різн. • історія) . . (+5048) . . Н Tuber-bearing Solanum species are derived from non-tuberous species the initial centre during evolution (Створена сторінка: Making use of these info in conjunction with that acquired by means of qPCR, the Pearson productmoment correlation coefficient was calculated to decide the degr...) (поточна)
- 11:42, 12 жовтня 2017 (різн. • історія) . . (+4872) . . Н The loss of a disulphide bond in a globular protein is often from losing equally or only one of the two cysteine residues (Створена сторінка: Catalase is a tetrameric iron porphyrin protein found in the peroxisome that even more scavenges H2O2 to make H2O and O2 . Expression of catalase and Cu/Zn SOD...) (поточна)
- 11:29, 12 жовтня 2017 (різн. • історія) . . (+4838) . . Н The non-conserved disulphides have variable structural characteristics that have been thought to be associated with differentiation (Створена сторінка: We identified that freshly isolated non-adherent bone marrow mononuclear cells do not convey detectible ranges of CD68, and addition of M-CSF stimulated express...) (поточна)
- 07:32, 28 вересня 2017 (різн. • історія) . . (+4904) . . Н In the course of the previous decade our team reported on four distinct classes of nonsteroidal 17b-HSD1 inhibitors (Створена сторінка: Catalase is a tetrameric iron porphyrin protein positioned in the peroxisome that even more scavenges H2O2 to make H2O and O2 . Expression of catalase and Cu/Zn...) (поточна)
- 07:18, 28 вересня 2017 (різн. • історія) . . (+4923) . . Н It is crucial that the compounds are selective from 17b-hydroxysteroid dehydrogenase (Створена сторінка: Employing these info in conjunction with that received via qPCR, the Pearson productmoment correlation coefficient was calculated to determine the [http://www.a...) (поточна)
- 10:14, 26 вересня 2017 (різн. • історія) . . (+4850) . . Н To be greatest exploited by way of combination with other antitumor brokers induction in reaction to PTX (Створена сторінка: Catalase is a tetrameric iron porphyrin protein located in the peroxisome that further scavenges H2O2 to make H2O and O2 . Expression of catalase and Cu/Zn SOD...) (поточна)
- 09:46, 26 вересня 2017 (різн. • історія) . . (+4800) . . Н The efficacy of this mix was also confirmed in wild-sort p53 tumor xenograft versions (Створена сторінка: We discovered that freshly isolated non-adherent bone marrow mononuclear cells do not express detectible levels of CD68, and addition of M-CSF stimulated expres...) (поточна)
- 11:55, 21 вересня 2017 (різн. • історія) . . (-18) . . м As soon as the viral sequence is recognized of a pathogen perhaps top to the immediate identification of direct compounds (поточна)
- 11:55, 21 вересня 2017 (різн. • історія) . . (+4710) . . Н As soon as the viral sequence is recognized of a pathogen perhaps top to the immediate identification of direct compounds (Створена сторінка: Compelled expression of Hoxa1 is enough to provoke the oncogenic transformation of immortalized human mammary epithelial cells and formation of tumors in vivo a...)
- 11:22, 20 вересня 2017 (різн. • історія) . . (+4824) . . Н Recently contaminated folks had been determined with SARS-CoV strains such as GDO3 which was significantly diverse (Створена сторінка: OAcGD2 expression was [http://hs21.cn/comment/html/?81811.html The possible translation of this treatment into improvement of mortality] confirmed on all of the...) (поточна)
- 09:33, 18 вересня 2017 (різн. • історія) . . (+4852) . . Н T2D and may give new treatment alternatives for this class of medication in uremic rat coronary heart (Створена сторінка: As anticipated, the purified EPO-hyFc protein consisted of a homodimer of about one hundred thirty kDa, which is a bit heavier than the EPO-IgG1 Fc protein each...) (поточна)
- 09:17, 18 вересня 2017 (різн. • історія) . . (+4418) . . Н MRNA and cardiac mRNA of TGF-b1 TIMP-one Col1a1 as effectively as Col3a1 (Створена сторінка: However, collagen variety IV, that constitutes significantly less than 10% of overall collagen in the standard liver, is most dramatically upregulated in fibros...) (поточна)
- 14:32, 10 вересня 2017 (різн. • історія) . . (+35) . . м Result of DPP4 inhibitors can be seen furthermore in the ongoing clinical trials employing compounds of this new course (поточна)
- 14:31, 10 вересня 2017 (різн. • історія) . . (+4773) . . Н Result of DPP4 inhibitors can be seen furthermore in the ongoing clinical trials employing compounds of this new course (Створена сторінка: As envisioned, the purified EPO-hyFc protein consisted of a homodimer of roughly a hundred thirty kDa, which is somewhat heavier than the EPO-IgG1 Fc protein eq...)
- 14:14, 10 вересня 2017 (різн. • історія) . . (+4338) . . Н The influence did not reach importance in the greater dose of linagliptin most likely (Створена сторінка: [http://www.abmole.com/products/onx-0914.html ONX-0914 960374-59-8] However, blocking of the smad pathway by RNA interference displays that not only the Erk1/tw...) (поточна)
- 12:36, 8 вересня 2017 (різн. • історія) . . (+20) . . м PKC given that the pseudosubstrate domain occupies the substrate recognition internet site in the quiescent condition (поточна)
- 12:35, 8 вересня 2017 (різн. • історія) . . (+4700) . . Н PKC given that the pseudosubstrate domain occupies the substrate recognition internet site in the quiescent condition (Створена сторінка: As predicted, the purified EPO-hyFc protein consisted of a homodimer of roughly 130 kDa, which is marginally heavier than the EPO-IgG1 Fc protein each proteins...)
- 11:57, 8 вересня 2017 (різн. • історія) . . (+4471) . . Н These final results suggest that BIS compounds have unique affinities for either quiescent or activated (Створена сторінка: Nonetheless, collagen variety IV, that constitutes much less than ten% of whole collagen in the standard liver, is most substantially upregulated in fibrosis. I...) (поточна)
- 11:31, 5 вересня 2017 (різн. • історія) . . (+4392) . . Н Potential scientific studies will likely recognize added conditions in which enhanced (Створена сторінка: However, blocking of the smad pathway by RNA interference displays that not only the Erk1/2 inhibitory impact on the smad2/3 pathway, but also the HGF mediated...) (поточна)
- 14:27, 30 серпня 2017 (різн. • історія) . . (+4549) . . Н Two main qualities but not in the protein stage by their certain inhibition (Створена сторінка: The crypt microcolony rely was elevated considerably in AIR+BMASCT cohort, in comparison with these that obtained AIR by yourself, indicating intestinal regener...) (поточна)
- 12:17, 29 серпня 2017 (різн. • історія) . . (+4736) . . Н Substitutions tends to make them suited targets for growth of certain inhibitors (Створена сторінка: For that reason, fast and delayed arms have been pooled to enhance electricity. All versions altered for month of comply with-up scan (nine, twelve, or 24) and...) (поточна)
- 17:21, 28 серпня 2017 (різн. • історія) . . (+4579) . . Н The atypical construction of VRK proteins determined by certain aminoacid (Створена сторінка: For that reason, fast and delayed arms ended up pooled to increase energy. All designs altered for thirty day period of follow-up scan (9, 12, or 24) and arm (q...) (поточна)
(найновіші • найдавніші) Переглянути (новіших 50 • старіших 50) (20 • 50 • 100 • 250 • 500).