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All these indicate the anemic condition and are commonly noted in patients with chronic arthritis.[17] The selected doses of PHF (250 mg/kg and 500 mg/kg) treated group showed a significant (P learn more levels compare to arthritic control. In arthritis condition there is a mild to moderate rise in WBC count due to release of interleukin-1 beta increase the production of monocytes and colony stimulating factor.[18] The administration of PHF reverses back the elevation of WBC levels to normal level. Table 4 Effect of the ethanolic extract of polyherbal formulation on hematological parameters Effect of polyherbal formulation on biochemical parameters of arthritic rats As a result [Table 5] of inflammation induced by adjuvant, the levels of AST, ALT and ALP were increased in all arthritis rats as compared to control rats. The PHF treated (at a doses of 250 and 500 mg/kg) animals showed significant Pictilisib mw (P from catalyzing oxidative damage. The ARAF increased level of copper ion indicates the inflammatory condition. Serum copper concentration was measured in normal and arthritic rats.[19] The arthritic rats exhibited a significant elevation of copper level and this was significantly (P