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Beta is measured in units of standard deviation, and value is a measure of how strongly each predictor variable influences the criterion (dependent) variable. Cohen��s standard for beta values above 0.10, 0.30, and selleck 0.50 represents small, moderate, and large relationships, respectively. Results The mean age of the study population was 59.7 years (women 59.2 years and men 60.0 years). The mean BMI of both men and women was 27.4 kg/m2 (Table 1). Fasting plasma glucose values were 6.0 mmol/L in women and 6.5 mmol/L in men. The use of antihypertensive, lipid-lowering, and antidepressant medications was higher in men and women with depression. Hs-CRP was not statistically different in men or women with or without depression. LTPA was significantly higher both in men and women without depression. BP was the same in all groups. Table 1 The basic demographic, lifestyle and biochemical characteristics of study population according to BDI-21 values DEF6 (TSH over and F-T4 under the reference rate) was 1.3%. The prevalence of these groups was the same in BDI-21 over and under 10 points compared to subjects with normal thyroid values. Table 2 shows that the prevalence of depressive symptoms (BDI-21 ��10 points) was 17.5% in women and 12.5% in men. The mean thyroid values for women without depressive symptoms (BDI-21 Beck Depression Inventory (BDI-21) scores learn more and thyroid values (TSH, F-T4, F-T3) in men and women. Table 3 shows that in multiple regression analysis, TSH has no relationship to BDI-21 total score. Table 3 Multiple regression analysis for BDI-21 total score. Discussion This study found no association between depressive symptoms and TSH, F-T4, and F-T3 in this Finnish population-based cohort. The prevalence of depressive symptoms was 17.5% in women and 12.5% in men. This is in line with other studies assessing depressive symptoms in Finland.8 The prevalence of hypothyroidism or subclinical hypothyroidism in this population, measured by s-TSH over the reference range 4.2 mU/L, was 5.5%. The calculated lifetime risk for developing overt hypothyroidism in Denmark was 2.3%, with a threefold excess in women (3.5% vs. 1.0% in men).9 We, like many others, excluded the persons (N = 79) who used thyroxine from the analysis.