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1, OSSTEM?, US II?) with different lengths (7, 10, and 13?mm) were used. IT was recorded automatically by a computer which was connected to the Implant fixture installation device during the placement. RFA was conducted to quantify the primary implant stability Isotretinoin quotient (ISQ). All two measurements were repeated 10 times for each group. All these differences were statistically significant between the two groups (P?INCB28060 molecular weight that primary implant stability seems to be influenced by the presence of a cortical plate and total surface area of the implant fixture appears to be the decisive determinant for ISQ value. ""This study was undertaken to evaluate the influences of concave, machined and concave-roughened profiles of transmucosal implant designs on early peri-implant tissue responses. Implants were used and classified by transmucosal profile and surface type as straight-machined implants (SM), concave-machined implants (CM), or concave-roughened implants (CR). A total of 30 implants (10 per each type) with matching transmucosal profiles were placed directly Akt inhibitor on alveolar crests in randomized order in the edentulous mandibular ridges of three beagle dogs. Healing abutments were connected 4?weeks after implant placement, and prostheses were connected 8?weeks after implant placement and functionally loaded. All animals were sacrificed at 16?weeks. Peri-apical radiographs were obtained and measured to evaluate peri-implant marginal bone levels. Histological specimens were prepared to measure bone resorption, connective tissue contact, epithelial tissue height, biological width, and length of implant-abutment junction to the apical portion of junctional epithelium. Radiographic and histometric analysis showed that least bone resorption occurred around CM implants and greatest bone resorption around SM implants (P?