CAPNS1 -- Turn Into A Expert In Five Quick Steps
The Spearman rank correlation coefficient was calculated to assess the relationship Talazoparib cell line between E2 and SDF-1 alpha. The mean serum SDF-1 alpha concentration was 2087.03 �� 550.03 pg/ml. SDF-1 alpha serum concentration did not significantly differ between smokers (2020.3 �� 470.39 pg/ml) and non-smokers (2101.97 �� 568.43 pg/ml, p = 0.606), obese (2184.74 �� 491.05 pg/ml) and non-obese (2051.21 �� 569.78 pg/ ml, p = 0.333), or statin users (2109.79 �� 499.29 pg/ml) and non-users (2064.65 �� 608.32 pg/ml, p = 0.717). The mean serum T level in the whole group was 12.25 �� 7.88 nmol/l. T concentration did not significantly differ between smokers (14.41 �� 8.92 nmol/l) and non-smokers (11.77 �� 7.62 nmol/l, p = 0.243), obese (10.82 �� 5.7 nmol/l) and non-obese (12.78 �� 8.52 nmol/l, p = 0.321), or statin users (12.59 �� 7.41 nmol/l) and non-users (11.94 �� 8.62 nmol/l, p = 0.719). The serum E2 level was 44.1 (32.3 �C 64.0 pmol/l). E2 concentration did not significantly differ between smokers 53.2 (32.5 �C 71.1 pmol/l) and non-smokers 44.7 (31.2 �C 63.6, p = 0.453), obese 51.5 (41.6 �C 64.9 pmol/l) and non-obese 42.35 (30.3 �C 61.0 pmol/l, p = 0.058), or statin users 42.0 (30.4 �C 56.0 pmol/l) and non-users 49.1 (33.5 selleck chemicals �C 64.1 pmol/l, p = 0.314). The mean serum SHBG was 31.38 �� 15.51 nmol/l. SHBG concentration did not significantly differ between smokers (31.69 �� 16.55 nmol/l) and non-smokers (31.31 �� 15.4 nmol/l, p = 0.933), obese (30.27 �� 10.37 nmol/l) and non-obese (31.79 �� 17.07 nmol/l, p = 0.698), or statin users (32.9 �� 15.89 nmol/l) and non-users (30.19 CAPNS1 �� 15.46 nmol/l, p = 0.442). The mean E2 to T ratio was 5.59 �� 3.28. The E2/T ratio did not significantly differ between smokers (5.33 �� 3.14) and non-smokers (5.65 �� 3.34, p = 0.738), obese (6.57 �� 3.62) and non-obese (5.23 �� 3.11, p = 0.104), or statin users (5.14 �� 3.12) and non-users (6.1 �� 3.48, p = 0.196). The only significant correlations observed were: a positive correlation between SDF-1 alpha and T (r = 0.233; p = 0.036); a positive correlation between SDF-1 alpha and SHBG (r = 0.312; p = 0.004); and an inverse correlation between SDF-1 alpha and E2/T ratio (r = -0.463; p = 0.000) (Fig. 1). There was no significant correlation between SDF-1 alpha and age (r = 0.093; p = 0.404), BMI (-0.001; p = 0.994), or E2 (-0.139; p = 0.212). The correlations between SDF-1 alpha and T, SHBG and E2/T ratio were also examined using multiple regression analysis (Tab. 2).
