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?3A,B). Under the age of 60?years, over 75% of asthmatics have physician��s diagnosed rhinitis. Watery rhinorrhea was present in around 60% of the patients with physician��s diagnosed rhinitis before the age of 60?years. After the age of 60?years, the prevalence of watery rhinorrhea decreased whereas the prevalence of rhinitis without rhinorrhea was similar in all age groups. Everolimus Watery rhinorrhea was less reported by patients than by physicians according to the self- and physician-administered questionnaires (r?=??0.238, P?Cilengitide those without rhinitis. The study included two sets of over 13?000 patients each using identical questionnaires for asthma and rhinitis. Similar results have been obtained in both populations showing the validity CDK inhibitor of results. The subjects included in this study were prediagnosed with asthma. The diagnosis of asthma was made according to the Japanese guidelines (16). These guidelines have been used by the vast majority of physicians in Japan for the past 15?years (23) and have been frequently updated. However, it is possible that, after 60?years of age, some COPD patients may have been diagnosed as asthmatics (24). The same questionnaire was self-administered and physician-administered. The questions were based on the two most widely used asthma [GINA (15)] and rhinitis [ARIA (1)] guidelines. All questions were filled in, and 26?680 (90.3%) patients had an evaluable questionnaire for the study purpose. Results of both questionnaires were similar. The severity and persistence of rhinitis was based on all ARIA questions (1). The control of asthma was based on GINA questions (15) but did not include pulmonary function (17). It is, therefore, possible that some patients were classified as ��controlled�� whereas they were not. However, most asthma control questionnaires do not use pulmonary function tests (25), and the ACQ (asthma control questionnaire) is more reliable without including data of pulmonary function tests than with them (26). Some questions of GINA control are not fully defined, and we needed to use a specific wording.