Eliminate Y-27632 Issues Totally

Clinical information was retrieved from the records of all dogs that were presented to the authors�� hospital for the surgical treatment of CCLR between 2002 and 2009. Data for analysis included patient signalment (age, breed and sex), duration of lameness, extent of CCLR and condition of the medial meniscus. The duration of lameness was that reported by the owners or referring veterinary surgeons. The extent of CCLR was determined from the surgical report and stifle manipulation during preoperative examinations under sedation or anaesthesia (McKee and Cook 2006, Carobbi and Ness 2009). ��Complete�� ruptures were grossly unstable stifles (cranial drawer and cranial tibial thrust positive) with surgical confirmation that no functional ligament remained intact. ��Partial�� ruptures were diagnosed in stable stifles (i.e. minimal/absent Fleroxacin cranial drawer or cranial tibial thrust in extension) with surgical confirmation of incomplete rupture. The condition of the medial meniscus was determined from the surgical report: either ��intact�� or ��torn.�� All cases underwent Y-27632 cost medial or lateral stifle arthrotomy, with or without meniscal probing, by a board-certified surgeon or senior resident. Dogs were excluded if clinical records were incomplete or if previous surgery had been performed on the affected stifle. Spreadsheet software (Excel 2003, Microsoft) was used for data management before further analysis using statistical software (GraphPad Prism 5.0, GraphPad Software Inc. (San Diego, CA, USA) and SPSS 16.0, SPSS Inc, Chicago, IL, USA). Categorical data were analysed using the chi-squared test. Ratio measurements were summarised as mean (��sd), tested for deviations from normality using the D��Agostino-Pearson test and then compared using either the t test or the Mann-Whitney test. All variables were examined with the CHIR 99021 null hypothesis of homogeneity between groups, with statistical significance taken as P��0��05 (two-tailed). Logistic regression was performed on variables thought to be associated with medial meniscal tears using forced-entry regression (entry criterion P