Evaluation - The MG-132 Benefits As well as Cons

The SD is a measure of variability and the RDW incorporates the SD into its calculation. The RDW may be impacted by various disease states and therefore may be useful in the diagnostic evaluation (10, 11). Main points Any set of measured values can be characterized in terms of its center and range of values, the range being a measure of variability. The range is characterized by the span between the least value and the greatest value. Variability is conveniently characterized by a measure of SD when a set of values is normally distributed. Acknowledgements The author gratefully acknowledges the contributions of the following individuals whose thoughtful reviews and constructive criticisms contributed to the completion of this document: Razvan Hurezeanu, MD; Alan T. Kaell, MD; Srinivas Madhavan, MD; and Ayesha Qadir, MD. Conflict of interest and funding The author has not received any funding or benefits from industry or elsewhere to conduct this study.""Ultrasound is becoming an indispensable diagnostic resource in medicine. It can be universally applied without contraindications, offers real-time imaging with easy bedside access and can be applied for interventional procedures through direct visualization (1). It is already well established for diagnostic and therapeutic use in various specialties, including physical medicine and rehabilitation, obstetrics and gynecology, and emergency medicine (2). The internal medicine specialties, including cardiology, endocrinology, rheumatology, nephrology, and pulmonary critical care are now using ultrasound as an extension of the physical examination and for interventions. There have been numerous studies evaluating incorporation of ultrasound training into these training programs (3, 4). The use of ultrasound, Mannose-binding protein-associated serine protease primarily for diagnostic and therapeutic musculoskeletal problems, has seen a surge among providers and hospitals (5�C7). Residents commonly use ultrasound limited to central line placement in the intensive care units and a few subspecialty areas based on interest. It is less common, however, for Internal Medicine Residency Training Program (IMRTP) to provide a formal training curriculum beyond these limited uses. Musculoskeletal problems are one of the most common reasons for ambulatory care visits in the United States, accounting for 8.3% of the 1.2 billion visits per year (8). According to the Centers for Disease Control, musculoskeletal and connective tissue diseases are also one of the most frequent diagnoses for emergency department visits, estimated at 8,239,000 (SD 498,000) visits annually �C about 6.3% (SD 0.2) of the total (9). These figures highlight the burden of musculoskeletal problems in both ambulatory and inpatient domains in the United States.