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In addition, the correlation between the PSQ and PCS was assessed using Pearson's correlation coefficient Dipivefrine to assess criterion validity (convergent validity). Values �� 0.40 were considered satisfactory (r��0.81�C1.0 as excellent, 0.61�C0.80 very good, 0.41�C0.60 good, 0.21�C0.40 fair, and 0.0�C0.20 poor) [13]. In addition, known-groups comparison analysis was performed to test how well the questionnaire discriminates between subgroups of patients who differed in the Finneson-Cooper score and between LDH group and normal cases. It was hypothesized that patients with a Finneson-Cooper ""good"" grade would achieve a greater increase in the PSQ score compared with cases with a Finneson-Cooper ""fair"" grade and the LDH group would report worse conditions on the PSQ compared to patients with normal cases. 7. Ethics The Ethics Committee of Shahid Beheshti University of Medical Sciences approved the study. Results In all 140 patients completed the questionnaire. The characteristics of patients and their scores on the PSQ and affected levels are shown in Table 1. The mean age of patients was 51.7 (standard deviation [SD]=8.9) years; most were married (77.1%), and had completed primary or secondary education (72.1%). Table 1 The characteristics of the study patients and their scores on the PSQ www.selleckchem.com/products/cx-5461.html (n=140) The internal consistency of the PSQ was found to be satisfactory reliability (Table 2). The Cronbach's alpha coefficient for the PSQ-minor, PSQ-moderate and PSQ-total was 0.80, 0.82 and 0.81, respectively. Further analysis also indicated that the test�Cretest ICC (95% confidence interval) was 0.84 (0.616�C0.932) for PSQ total, 0.85 (0.645�C0.941) for PSQ-minor, and 0.84 (0.621�C0.936) for PSQ-moderate for LDH group (n=89), lending support to its good reliability. Table 2 Test�Cretest reliability results for the PSQ-minor, PSQ-moderate and PSQ-total scores for LDH group (n=89) Validity of the PSQ was examined using item-scale correlations. The item-scale correlation matrix between each item and the two PSQ subscales based on LDH disease are shown in Table 3. All correlations between items and its hypothesized scale showed satisfactory results suggesting that the items had a substantial association with the subscale representing the concept. Pearson correlation coefficient exceeded Forskolin in vivo the 0.40 level recommended ranging from 0.51 (Q10) to 0.82 (Q4). In addition, the PSQ demonstrated a significant positive correlation with PCS lending support to its good convergent validity (r=0.81; p