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To avoid global correlations, the associations were assessed in the patient sample. Predictive validity Participants were exposed to rapid visual serial presentation of emotionally arousing and neutral pictures from the International-Affective-Picture-System (Lang, Bradley, & Cuthbert, 2008). Following exposure, a psychologist interviewed the participants about their shutdown dissociative responding. The tendency towards shutdown dissociation was rated on a Likert scale with possible scores of 0 (not at all), 1 (a little bit), 2 (moderately), 3 (strongly), and 4 (very strongly) during picture presentation Oxymatrine using the 13-item Shut-D Intensity Scale. Although the unpleasant pictures were not personalized for the traumatic events, 60% of the PTSD sample experienced intrusive memories of their own trauma that were triggered by the stimulation (Schalinski et al., 2014). Results Reliability Internal consistency We performed a principal axis factoring analysis using the Kaiser�CGuttman criterion to determine the factor structure in the data of the samples 1�C4 (n=293). The first factor (eigenvalue 5.65) accounted for 43.43% of the variance, whereas the second factor (eigenvalue 1.07) accounted for 8.19% of variance. All other eigenvalues were below 1. Table 3 presents the factor loadings of the items as well as the rotated factor solution (Varimax procedure). The internal consistency of the scale was examined with Cronbach's ��. The questionnaire showed excellent internal consistency with Cronbach's ��=0.89 in its original item composition. The internal consistency could not be improved through item deletion. Table 3 Item difficulties and factor loadings Verubecestat in an one-factor solution as well as in a rotated (Varimax) two-factor solution Item-total correlation The item-total correlation was performed in the whole sample. All Shut-D item-to-total correlations were significant at psee more Test�Cretest reliability The study sample consisted of 50 participants (38 patients with PTSD and/or depressive disorders according to the criteria of the DSM-IV) and 17 healthy controls. The mean shutdown dissociation score at the first assessment was M=15.1 (SD=9), and M=17.14 (SD=9.13) at the second assessment, whereas the healthy control group reported significantly lower scores upon the first (M=0.83, SD=1.17) and second assessments (M=0.81, SD=1.03). The length of the test�Cretest interval was on average M=39 days and SD=27 (range 7 and 134 days).