Hilarious Tweets Regarding Alectinib
Neither of the two patients with Mycobacterium abscessus bacteraemia received appropriate therapy, and both died. Among HIV-infected patients, the MTB cases had higher CD4 counts (18.4��?8.3 vs. 7.6��?.0; p?.145) and a lower mortality rate (16.7% vs. 33.3%; p?.280) than the MAC cases, although the differences were not statistically significant. Forty-three of 47 (91.5%) patients who received highly active antiretroviral therapy had a higher CD4 count (11.3��?2.7 vs. 3.3��?.7; p?.297) and a lower mortality rate (25.6% vs. 50.0%; p?.308) than those who did not receive highly active antiretroviral therapy, but the difference was not statistically significant. In conclusion, the clinical characteristics of mycobacterial bacteraemia in HIV-infected patients and patients not infected with HIV were different. HIV-infected patients had better outcomes, were younger, had fewer underlying diseases Alectinib and better PI3K inhibitor drugs nutritional status; and were also more likely to have MAC bacteraemia than MTB bacteraemia. This study was partly supported by the Institute for Biotechnology and Medicine Industry, Taiwan (DOH97 -DC-1501). The sponsor did not participate in the following: design or conduct of the study; collection, management, analysis or interpretation of the data; and preparation, review or approval of the manuscript. All authors declare no conflicts of interest. ""Clin Microbiol Infect 2011; 17: 80�C87 Our objective was to assess junior doctors�� perceptions of their antibiotic prescribing practice and of bacterial resistance. We surveyed 190 postgraduate doctors still in training at two university teaching hospitals, in Nice (France) and Dundee (Scotland, UK), and 139 of them Tryptophan synthase (73%) responded to the survey. The main results presented in this abstract are combined for Nice and Dundee, because there was no statistical difference for these points between the two hospitals. Antibiotic resistance was perceived as a national problem by 95% of the junior doctors, but only 63% rated the problem as important in their own daily practice. Their perceptions of the causes of antibiotic resistance were sometimes at variance with available medical evidence, with excessive duration of antibiotic treatment and poor hand hygiene practices rarely being perceived as important drivers for resistance. Only 31% and 26% of the doctors knew the correct prevalences of antibiotic misuse and of methicillin-resistant Staphylococcus aureus in hospitals, respectively. They preferred educational interventions, such as specific teaching sessions, availability of guidelines or readily accessible advice from an infectious diseases specialist, to improve antibiotic prescribing, rather than restricted prescription of antibiotics. These data provide helpful information for the design of strategies to optimize adherence to good antimicrobial stewardship.