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Patients treated with short-term PN (http://www.selleckchem.com/products/r428.html weight loss. In addition, the team recommended that lipid therapy in patients receiving long-term PN be restricted to twice-weekly administration (Mondays and Fridays) with a maximum daily dose of 50�g. Critically ill patients treated with the sedative propofol (Diprivan, Hospira Inc., Lake Forest, IL) or the antihypertensive clevidipine (Cleviprex, The Medicines Company, Parsippany, NJ) did not receive lipids because these drugs provide 1.1 and 2�kcal/ml, respectively, of lipid calories.[19, 20] Calcium gluconate is the preferred form of calcium supplementation E-64 for PN therapy and for intravenous administration to correct severe deficiencies and prevent or treat cardiac arrhythmias.[21] Intravenous calcium gluconate went on shortage in August 2010 because two manufacturers discontinued production, and demand outstripped available supplies.[1] Hospital-wide calcium restrictions were implemented in order to meet the needs of patients in greatest need. Rather than adding calcium to PN therapy, it was administered by intravenous bolus for patients meeting certain criteria. Therapy was converted to oral calcium if at all feasible. Intravenous calcium supplementation with the gluconate or chloride salts was approved for symptomatic patients with hypocalcemia (ionized calcium see more bleeding requiring transfusion. Intravenous calcium was also allowed for patients undergoing parathyroidectomy.[21] Because of a secondary shortage, the alternative intravenous calcium supplement, calcium chloride, was only permitted in the intensive care unit and with restrictions similar to calcium gluconate. Calcium chloride, as an alternative to the gluconate salt, may be used in parenteral nutrition under rare circumstances (neonates, pediatric patients, and patients with severe symptomatic hypocalcemia). However, it is important to note that calcium chloride significantly alters the calcium-phosphate compatibility curves.[22] The sulfate salt is the available choice for administration of intravenous magnesium.