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Out of eight variables tested, significant association was observed with male gender (RR = 1.12; 95% CI 1.02�C1.24), age at diagnosis 10 years, BMI PR-171 concentration = 2.06; 95% CI 1.56�C2.73), habitual khat chewing (AOR = 1.74; 95% CI 1.33�C2.28), and BMI YES1 (AOR = 1.37; 95% CI 1.063�C1.773). Table 3 Multivariable logistic regression analysis of variables independently related to poor glycemic control defined as HbA1c > 9.0%. We also checked HbA1c between KC and NKC in patients using different medications for diabetes. The largest group was of patients not on medications (n = 374), of which 254 were KC and 120 NKC. In this group, the mean HbA1c among the KC was 10.7% (SD 2.9) and among the NKC was 9.6% (SD 2.8); P value was 0.006. The second group of patients was those on sulfonylureas (n = 182), of whom 132 were KC and 50 were NKC. In this group of patients, the mean HbA1c of the KC was 10.7% (SD 2.7) and of the NKC was 9.7% (SD 1.9); P value was 0.003. The third group of patients was those on metformin (n = 173), of whom 104 were KC and 69 were NKC. In these patients, the mean HbA1c was 8.2% AZD9291 nmr (SD 2.2) for the KC and 7.7% (SD 2.0) for the NKC; P value was 0.464. The fourth group of patients was of those being treated with insulin (n = 172), comprising 95 KC and 77 NKC. In these patients, the mean HbA1c was 9.9% (SD 2.5) for the KC and 9.3% (SD 2.2) for the NKC; the P value was 0.567. Khat chewing and age of diagnosis of type 2 DM The mean age of diagnosis of type 2 DM among the khat chewing group was 43.3 (10.1), whereas that among the non-chewing group was 45.9 (11.8) (P