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7 to 1.7/100?000, p?Terminal deoxynucleotidyl transferase 35B. This is not reassuring because only 19A is included in PCV13. Birinapant concentration In France, a less significant decline (18%, p?0.03) was observed in children��s pneumococcal meningitis rates after the introduction of PCV7, especially in children 20% (95% CI 1.5�C35.2). In a Cochrane review the relative reduction of acute otitis media was between 6% (95% CI ?4 to 16) and 7% (95% CI 4.1�C9.7) in PCV7-vaccinated children selleck screening library million in 2004, all ages combined [96�C98]. The ecological niche of S.?pneumoniae is the nasopharynx [99]. Although not the main objective of pneumococcal vaccines, their efficacy in decreasing carriage has been disappointing. Some researchers found a decrease of the vaccine serotypes in colonization (p?