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P value?=?0.02 ( Table 4). One COA patient who was pre-term (35?weeks), very sick preoperatively with multiorgan dysfunction and requiring inotropes, died post operatively due to Acinetobacter septicemia. Complications like stridor, low cardiac output state, diaphragmatic paralysis, septicemia, new onset of seizure, pleural effusion, acute kidney injury and chylothorax were more prevalent in the Verteporfin concentration LBW group, but did not reach statistical significance. Only the number of re-intubations was statistically significant in Group A: 18 out of 37 (48.6%) in comparison to Group B: 8 out of 39 (20.5%) (p?=?0.015) ( Table 4). In the early era of cardiac surgery, LBW infants were treated either medically, considered inoperable, or were candidates solely for palliative procedure. The immaturity of the organ systems of LBW infants, including lungs, liver and, most importantly, neurologic development puts them at risk for many types of morbidity after pediatric cardiac surgery [1]. Indeed, non-cardiac factors may be associated with low birth weight, and may jeopardize the outcome of surgery, thus requiring careful evaluation [8]?and?[9]. In previously reported studies that assessed the effect of patient size on outcomes after repair of coarctation, mortality was much higher in LBW infants ranging from 5% to 15% [13], [19], [20]?and?[21] compared with mortality rates of less than 2% for repair of isolated coarctation in full term infants with normal body weight [17], [18]?and?[19]. In a study by McElhinney et al. Bleomycin price low weight infants had a mortality of 14%, whereas no death was reported Mephenoxalone among larger weight infants [19]. More recently, with developments in the ICU field, the technology of cardiopulmonary bypass, techniques of cardiac surgery, and advancement in post operative care, an improvement in results with more encouraging outcomes has been achieved [8]. In 2008, Curzon et al. published an important report of the Society of Thoracic Surgeons Congenital Heart Surgery Database where they analyzed outcomes of cardiac surgery in infants with LBW (