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Data were prospectively collected by use of a form based on the Utstein-style reporting guidelines for OHCA,12 13 including age, sex, PD0325901 origin of CA, location of arrest, disabilities in daily living, EMS dispatcher-assisted CPR instruction, bystander-initiated CPR, first documented rhythm, time course of resuscitation, advanced airway management, intravenous fluids and epinephrine, as well as prehospital return of spontaneous circulation, 1-month survival and neurological status at 1?month after the event. Both chest compression-only CPR and conventional CPR with rescue breathing were considered as layperson CPR. Rescue breathing without chest compression was classified as no CPR. The outcome was assessed by the health style according to the Glasgow�CPittsburgh overall performance category (OPC)12 13 at 1?month after the event. Good neurological outcome was defined as OPC 1 or 2. Along with those Utstein data, we collected information regarding how laypersons described the breathing styles of CA victims. We collected the data from the anonymous written reports of emergency calls composed by each EMS dispatcher who actually took the emergency calls. EMS dispatchers asked for the callers for details of the victims�� responsiveness and breathing status routinely and recorded it on the report form. Data were presented as medians and IQRs for continuous variables and numbers and percentages for categorical variables. Groups were compared using Mann�CWhitney U test and ��2 test. Multiple logistic regression analysis assessed the factors associated with layperson-performance of CPR; adjusted ORs (AORs) and their 95% CIs were calculated. Potential EPZ-6438 solubility dmso confounding factors that were biologically essential DEF6 or significantly associated with layperson-performance of CPR at p