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A secondary aim was to possibly help define criteria for more selective imaging of trauma patients. MATERIALS Epacadostat concentration AND METHODS Study design This study was approved by the Yale University Human Investigations Committee. Review of the trauma registry (TraumaBase, Denver, CO) identified all adult blunt trauma patients admitted to Yale New Haven Hospital, an American College of Surgeons verified and Connecticut Department of Health designated urban level I trauma center, between October 2007 and October 2012. Demographic data, length of stay, injury severity scores (ISS), ASOI (liver and spleen) as well as the presence and locations of rib fracture(s) were abstracted. The location of rib fractures was extracted from chest radiography and/or CT scan imaging obtained at the time of admission. Rib fractures were classified as upper (1-2), middle (3-7) and MG 132 lower (8-12). Statistical analysis Statistical analysis was performed using IBM SPSS Statistics 19 (IBM Corporation, Somers, NY, USA) using a two-tailed Student's t-test and Chi-square as appropriate; statistical significance was assumed for P ATPase of patients with and without rib fractures The presence of lower rib fractures on CXR correlated with the presence of ipsilateral ASOI. The presence of any right sided rib fracture on CXR correlated with an increased incidence of liver whereas the presence of any left side rib fracture correlated with an increased incidence of spleen injury (both P