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However, ��open access�� does not mean ��free��. It costs money.11 Obviously, open access publishers promote creating institutional funds to support publishing fees in these journals and thereby avoid burdening research projects or individual researchers.12 Thus, a paradigm shift exists. A few years ago, the not-so-rich institutions Selleckchem JQ1 or countries could not access scientific journals in which they could publish their research; with this new publishing system, the not-so-rich institutions and countries cannot publish their research, although they can read others�� research. Let us be honest: ��Medical journals are undergoing a major change in the business model��.13 The defense of any of these two models is not associated with benefits to researchers, readers, or science in general. We are merely discussing who should pay E-64 and how the money should be paid. This controversy is purposively ignoring the origin of the majority of the traditional scholarly journals: institutional journals created by scientific or professional societies. When many of these journals were created, distribution costs were relevant; consequently, many of them required subscription fees, especially to non-members. With the new technology (the Internet), distribution costs tend to zero, and the other costs are acceptably low for many societies.14 Indeed, the two most important intervenients in the scholarly publication are not reimbursed at all: authors work for free, and reviewers work for free. So, why do we insist on keeping this confusing and misleading terminology? First, we should remember that several of the original signatories of the Budapest Open Access Initiative were staff members of business corporations directly involved in publishing journals through this new open access system. Unfortunately, no conflict of interest was ever declared in the declaration. Second, this terminology supports the not-sufficiently-discussed axiom that scholarly publishing should TAM Receptor inhibitor be professionalized by one of these two business models. A different and much simpler terminology might be used: gratis vs paid journals (Figure 1). Figure 1 A clearer terminology for the different publishing systems regarding to payments. Pharmacy Practice is a gratis journal, for which no one pays any fees or receives any compensation for their work. Pharmacy Practice can exist because of the collaboration with the following groups: Authors who submit their contributions without expecting anything else besides publishing their works; Peer reviewers who produce reports on the articles received without expecting anything else, thereby keeping the publishing wheel spinning; and Editorial and Advisory board members who make decisions and provide comments to oil the publication wheels without receiving any reimbursement. This arrangement is in agreement with the definition of a different scholarly publishing model: collaborative publishing.