Ridiculous Pictilisib Specifics And The Way It May Possibly Have An Impact On Users

5-1.5 mg/kg, targeting BIS between 60-70. Once the target BIS was attained, the infusion of the scheduled study drug (as per group allocation) was started. An experienced Endoscopist (Gastroenterologist with minimum 5 y of endoscopy experience) then commenced the procedure. Any increase in the BIS value above the target range was managed by administering incremental i.v. propofol boluses (20 mg increments) and propofol bolus administration was with held when BIS of the scheduled drug was stopped and BIS value allowed equilibrating above 80. Patients oropharynx thoroughly suctioned, turned supine with head up tilt (15 degrees), allowed for complete recovery with end points being eye opening on command, ability to handle secretions, follow simple commands, hemodynamic stability, Ceritinib maintaining room air saturation >95% and attainment of BIS value >90. Patients were shifted to the recovery room, kept in propped up position, oxygen supplementation via face mask (5lit/min), maintenance intravenous fluid (ringer lactate/ 0.9% saline) and continuation of standard monitoring was done. Recovery characteristics were noted using Modified Aldrette Score (MAS) [9] & Observer Assessment of Alertness and Sedation score (OAAS score) [10] and patient was discharged after documenting time taken for attainment of MAS > 9 and an OAAS score > 4, along with a responsible attendant. Outcome Measurements Primary-The total propofol consumption in each study group Secondary-1) Recovery profile of patients in each study group 2) Haemodynamic profile of patients in each study group Statistical Analysis All quantitative and continuous variables such as age, weight, vital parameters, utilizing descriptive statistics, were expressed as mean �� standard deviation. Mean differences between the groups were compared using ANOVA / Kruskal Wallis test. Mixed Model was used to distinguish the mean difference in hemodynamic variables among the 3 groups by taking treatment as fixed effect and time as random effect. p