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We subsequently examined allelic frequencies of HLA-DR HLA-DP, and HLA-DQ in mold-sensitive moderate-severe asthmatics (Table?2). The frequencies of HLA-DP alleles were not significantly different when comparing the groups (data not shown). Chi-squared test for independence was used for multiple comparisons of HLA-DRB1*13. Results were not significant for the percentages of patients and allele frequencies of HLA-DRB1*13 (P?>?0.05). However, comparison FXR of HLA-DRB1*13 was present in 38% of mold-sensitive moderate-severe asthmatics compared to 20% of mold-sensitive mild asthmatics (P? compared to mold-sensitive mild asthma, 0.199 vs 0.110 (P?CB-5083 molecular weight HLA-DRB1*13 ranged from 0.005 of 1330 individuals in North America (P? compared to mold-sensitive mild asthmatics, 29%vs 20%. When Alternaria-sensitive asthmatics were examined separately, a similar increase was found for HLA-DRB1*03, Selleck Motolimod 29%vs 20% of patients. Chi-squared test for independence was used for multiple comparisons of HLA-DQB1*03. Results were significant for the percentages of patients and allele frequencies of HLA-DQB1*03 (P?=?0.0084 and P?=?0.0133, respectively). The allele frequency of HLA-DQB1*03 was significantly decreased in mold-sensitive moderate-severe asthmatics compared to mold-sensitive mild asthmatics, 0.243 vs 0.381 (P?