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We acknowledge this GDC-0449 purchase as an important limitation. In our cohort, three participants (42.9%) did not have Internet or telephone access, and home visits were the only viable option. In summary, the steps to implement the OHC program involved the following: establishing the goal of true person-centered care and providing access to health care for those in need, creating an action plan to implement a timeline to accomplish setting-up and maintaining the program, exploring local sources of funding as well as securing volunteer commitments from multidisciplinary experts and from movement disorders fellows, meeting with the university administration and members of the community to discuss implementation of the project and also establishing access to the existing electronic medical record, recruiting qualified persons with PD and initiating home visits, implementing evaluations of effectiveness of the program through measures such as the UPDRS, hospital emergency visits, and CGIS, presenting cases to an interdisciplinary team in an open video and discussion format. Barriers to replicating this program include financial cost (travel and specialist time) and availability of qualified personnel. The current project (OHC) was funded through philanthropy, and that approach may not be feasible for expanding future home visit type programs. Another barrier will be obtaining an institutional commitment to allow medical records to be generated and maintained. Additionally, telemedicine will be able to reach some but not all of the patients in need. Finally, future studies will need MS-275 manufacturer to explore the detailed economic benefits of a PD Operation House Call program and will need to factor in the cost of having a movement disorders fellow and also a multidisciplinary team involved. Quinapyramine Additionally, other intangible factors such as loss of time from a clinic or hospital based practice must be more carefully accounted. These types of home-based programs may have the potential to reduce nursing home placement, morbidity, mortality, and hospitalization and possibly improve motor and quality of life; however, there is an important need for larger prospective studies in the home setting. The development of person-centered outcome metrics will aid in motivating government sources and insurance carriers to reimburse home care in PD. The OHC program, though small, has been beneficial to our local PD community in providing true person-centered access to care for those who could not otherwise access services. The future viability of this model of patient care will have to be tested with a much larger population. Acknowledgments The authors would like to acknowledge the Smallwood Foundation, the University of Florida Foundation, and the National Parkinson's Foundation for their logistical and financial support for Operation House Call. Disclosure Dr. Michael S.