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0 (GraphPad Software Inc., San Diego, CA, USA). Data are presented as means �� SD unless otherwise noted. Data with three or more groups were analysed using ANOVA followed by Tukey's post hoc test. A P value Torin 1 research buy remained viable up to 60 min of incubation in either 200 or 500 ��m CDME (Fig. 1A); therefore, similar conditions were used to assess the effects http://www.selleckchem.com/products/ABT-737.html of CDME on intracellular cystine levels and in subsequent experiments. As expected, incubation of cells in either 200 or 500 ��m CDME markedly increased the intracellular cystine levels by approximately fivefold (P Hesperadin of cells in either 200 or 500 ��m CDME significantly increased the total GSH content [10.3 �� 0.3 (P